DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fra and AgaP_AGAP012441

DIOPT Version :9

Sequence 1:	NP_523716.2	Gene:	fra / 36377	FlyBaseID:	FBgn0011592	Length:	1526	Species:	Drosophila melanogaster
Sequence 2:	XP_313213.4	Gene:	AgaP_AGAP012441 / 1274136	VectorBaseID:	AGAP012441	Length:	268	Species:	Anopheles gambiae

Alignment Length:	267	Identity:	57/267 - (21%)
Similarity:	82/267 - (30%)	Gaps:	109/267 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 ETYLLP----GQTAYFRCMLGEANWQEGVKHSVQWL--KDDLPLPL--------DKLRMVVLPNG 202
            |.|.|.    |.||:..|.:....  |||   |.|:  ||...|.:        ::.....|.|.
Mosquito     8 ENYTLVTSQIGSTAHVPCRIHHIG--EGV---VSWIRRKDYHLLTVGLTTYSSDERFSATHLQNS 67

  Fly   203 ---ALEIDEVGPSDRGSYQCNVTSGSSSRLSSKTNLNIK-KPSDPGAENSVAPSFLVGPSPKTVR 263
               .|:|..|...|.|.|:|.|::      ...|::.:: |..:..||       :|||..|.:.
Mosquito    68 EDWTLQIKFVQDRDAGLYECQVST------HPPTSIFLELKVVEARAE-------IVGPQVKYLT 119

  Fly   264 EGDTVTLDC--VANGVPKPQIKWLRNGMDLDFNDLDSRFSI------------------------ 302
            ...|:.|.|  |.:......|.|..|...::: |||...::
Mosquito   120 PDSTLKLICRVVQSTEASAFIFWYHNNRMINY-DLDRGINVSTEAEETTVQFGMRFLFDTISNIM 183

  Fly   303 ----------------------VGTGSLQ------------------------ISSAEDIDSGNY 321
                                  .||.||.                        ||.|....||||
Mosquito   184 LRSQADGVSSCLFRSGFGQHVAYGTESLHVYGLYSTPLSQPLALKDFHYSELTISQASKEHSGNY 248

  Fly   322 QCRASNT 328
            .|..||:
Mosquito   249 TCVPSNS 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fra	NP_523716.2	Ig	36..140	CDD:299845
		Ig	<180..222	CDD:299845	14/54 (26%)
		IG_like	257..340	CDD:214653	26/144 (18%)
		IGc2	264..327	CDD:197706	22/134 (16%)
		I-set	344..430	CDD:254352
		Ig	363..428	CDD:299845
		FN3	611..703	CDD:238020
		FN3	711..799	CDD:238020
		FN3	806..897	CDD:238020
		FN3	908..989	CDD:238020
		FN3	1011..1097	CDD:238020
		FN3	1109..1205	CDD:238020
		Neogenin_C	1273..1521	CDD:284094
AgaP_AGAP012441	XP_313213.4	Ig	13..94	CDD:299845	22/91 (24%)
		IG_like	13..90	CDD:214653	21/81 (26%)
		Ig	<233..255	CDD:299845	9/21 (43%)
		IG_like	<233..255	CDD:214653	9/21 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910