DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fra and AgaP_AGAP002708

DIOPT Version :9

Sequence 1:	NP_523716.2	Gene:	fra / 36377	FlyBaseID:	FBgn0011592	Length:	1526	Species:	Drosophila melanogaster
Sequence 2:	XP_312220.4	Gene:	AgaP_AGAP002708 / 1273260	VectorBaseID:	AGAP002708	Length:	382	Species:	Anopheles gambiae

Alignment Length:	336	Identity:	71/336 - (21%)
Similarity:	112/336 - (33%)	Gaps:	126/336 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 AYFRCMLGEANWQEGVKHSVQWLK---DDLPL-----------PLDKLRMVVLPNGALEIDEVGP 211
            |...|.:|...     ..:|.|::   |.:.|           |..|::.....|..|.|:.:..
Mosquito    74 AILNCRVGMLK-----DKTVMWIRRTTDKVSLLTVGNNTYSGDPRIKVKFQYPNNWRLHINPIKS 133

  Fly   212 SDRGSYQCNVTSGSSSRLSSKTNLNIKKPS-----DPGAENS---------------VAPSFL-- 254
            .|.|.|.|.|::......:  |||.:.:|:     :.|.|.|               |:.|:|
Mosquito   134 DDAGLYMCQVSTHPPRVFA--TNLTVLEPAVRIVDEMGYEFSDRYYKLGSTIEISCQVSTSYLAT 196

  Fly   255 VGPSPK----------------------TVREGDTVTLD--CVANGVPKPQIKWLRNGMDLDFND 295
            :.||||                      |.:.|...|.|  .:::...:..|.|.::|.:|   .
Mosquito   197 LPPSPKSAGQQQRSKTSPVGASANALDETAKTGSKATKDDNKLSDSTERGLISWTKDGAEL---P 258

  Fly   296 LDSRFSIVGT-----GSLQISSAEDIDSGNYQCRASNTVDSLDAQATVQVQEPPKFIKAPKDTTA 355
            .|.:.|..||     ..:.|..|..:.:|.|.|    ||....:|| .|||
Mosquito   259 KDVKMSFSGTKQWLISRISILQANRVHNGVYNC----TVAGKQSQA-AQVQ-------------- 304

  Fly   356 HEKDEPELKCDIWGKPKPVIRWLKNGDLITPNDYMQLVDGHNLKILGLLNSDAGM---FQCVGTN 417
                                  :.||:  || ..:|...||:::..||:    |:   |.|....
Mosquito   305 ----------------------VLNGE--TP-AAVQHNFGHHIEATGLV----GLHCPFWCGTLY 340

  Fly   418 AAGSVHAAARL 428
            :.|||.....|
Mosquito   341 SFGSVRVGLEL 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fra	NP_523716.2	Ig	36..140	CDD:299845
		Ig	<180..222	CDD:299845	13/55 (24%)
		IG_like	257..340	CDD:214653	25/111 (23%)
		IGc2	264..327	CDD:197706	16/69 (23%)
		I-set	344..430	CDD:254352	16/88 (18%)
		Ig	363..428	CDD:299845	15/67 (22%)
		FN3	611..703	CDD:238020
		FN3	711..799	CDD:238020
		FN3	806..897	CDD:238020
		FN3	908..989	CDD:238020
		FN3	1011..1097	CDD:238020
		FN3	1109..1205	CDD:238020
		Neogenin_C	1273..1521	CDD:284094
AgaP_AGAP002708	XP_312220.4	IG_like	74..157	CDD:214653	20/89 (22%)
		Ig	<90..158	CDD:299845	16/69 (23%)
		I-set	<248..305	CDD:254352	20/100 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910