DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8569 and zmynd8

DIOPT Version :9

Sequence 1:	NP_610795.1	Gene:	CG8569 / 36376	FlyBaseID:	FBgn0033752	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	XP_692886.6	Gene:	zmynd8 / 564460	ZFINID:	ZDB-GENE-041119-1	Length:	1201	Species:	Danio rerio

Alignment Length:	467	Identity:	95/467 - (20%)
Similarity:	155/467 - (33%)	Gaps:	146/467 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 KVSRLPSSPIDP---------FCFECHLPGAVKKCISCHRSFHENCQR--QDPEKPNYSVPSDKG 126
            |...|.:.|:|.         :|:.||..|.|..|..|.|.:|..|.:  .:||...:....:|
Zfish    90 KQPALTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLKLAAEPEGDWFCPECEK- 153

  Fly   127 QPYQFPVNELDNQPLNNTQNLETPQTPTPLLDHNSNINQTLLATTDFLKHENIEWDDDVFFVCEQ 191
                          :...:.:||......:|        ||               |.:.|:.:
Zfish   154 --------------ITVAECIETQSKAMTML--------TL---------------DQLSFLLK- 180

  Fly   192 KGARQRKLPRIKDELQSSLDSDEGSDLERCTHCRLLALAALHNPPQLDKQELGCLLKYSWDQHHS 256
                                               .||..:..|.....|:     ..|.:||
Zfish   181 -----------------------------------FALQKMKQPGTEPFQK-----PVSLEQH-- 203

  Fly   257 WISMDVAKYMAKHWNERDKALVKRLLFKTKILGLGDIERNIAAAKYTYLTEFLMDLLDLQHNMAV 321
               .|.|:|                :|..  :.:..:|:||....|.....||.|:..:.||..:
Zfish   204 ---PDYAEY----------------IFHA--MDICTLEKNIKKKMYGSTEAFLADVKWILHNCII 247

  Fly   322 FFGQKSVEYNATKWLMRDVTHDIREIRRCPDCYRYSNEASLSDLWFAKPCLQRHELVFAKQVGSP 386
            :.|.........|.:::...|::.||..||:|  |.:.....|.||.:||...|.||:||..|.|
Zfish   248 YNGGNHKLTATAKVIVKICEHEMNEIEVCPEC--YLSACQKRDNWFCEPCSNPHPLVWAKLKGFP 310

  Fly   387 PWPAKVMSVSKRQPIKYDVRFFGGTHSRALISERDITPIESDIQSHIKPRNSRALSAAIKELQCH 451
            .||||.:.....|   .|.||| |.|.||.:...:...:..:|...:|...| ..::|::|::.:
Zfish   311 FWPAKALRDKDGQ---VDARFF-GQHDRAWVPINNCYLMSKEIPFSVKKTKS-IFNSAMQEMEVY 370

  Fly   452 MMLSHYSASLFGF--HADPTVAENLIKVALSHCTESTETSASGKRGRPPTPATPGAA-----KNR 509
            :........:|.:  ...|...:|..::.|.                   ||.|.|.     |..
Zfish   371 VENIRKKFGVFNYAPFRTPYTPDNQFQMLLD-------------------PANPSAGSVKPEKQE 416

  Fly   510 RLNNTTSNTSSP 521
            ::......|:||
Zfish   417 KIKFNFDVTASP 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8569	NP_610795.1	PHD_SF	85..120	CDD:304600	12/36 (33%)
		Bromo_ZMYND11	243..350	CDD:99924	21/106 (20%)
		BS69_related	366..451	CDD:99902	29/84 (35%)
		zf-MYND	570..604	CDD:280009
zmynd8	XP_692886.6	TNG2	<11..154	CDD:227367	17/78 (22%)
		PHD_PRKCBP1	111..151	CDD:277013	12/39 (31%)
		Bromo_RACK7	172..270	CDD:99940	26/176 (15%)
		BS69_related	290..370	CDD:99902	29/84 (35%)
		DUF3544	449..639	CDD:288884
		DUF1640	1011..>1102	CDD:285090
		zf-MYND	1106..1140	CDD:280009
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D183667at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920