DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment achi and TGIF2LX

DIOPT Version :9

Sequence 1:	NP_001286352.1	Gene:	achi / 36373	FlyBaseID:	FBgn0033749	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_620410.3	Gene:	TGIF2LX / 90316	HGNCID:	18570	Length:	241	Species:	Homo sapiens

Alignment Length:	174	Identity:	62/174 - (35%)
Similarity:	91/174 - (52%)	Gaps:	33/174 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LENEGRGRFHSDSSLDQDSLHADVIVEEDQSTEHGANQVQNYHDMMVDSEHHIDINGSL------ 93
            :|....|...:.|.:::||         ...|:..|      .|..:.|.::.|....|
Human     1 MEAAADGPAETQSPVEKDS---------PAKTQSPA------QDTSIMSRNNADTGRVLALPEHK 50

  Fly    94 RKRRGNLPKTSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPEMIRR 158
            :||:||||..|||||:.|:|:||:.||||:.||..||::.||::||:.||||||||||||:|:::
Human    51 KKRKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLQISNWFINARRRILPDMLQQ 115

  Fly   159 EGNDPL--HFTISRRGKKVSPNCSRSSALGANLTGPNPAHGSPA 200
            ..|||:  |.|    ||.......:|:....      ||...|:
Human   116 RRNDPIIGHKT----GKDAHATHLQSTEASV------PAKSGPS 149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
achi	NP_001286352.1	Homeobox_KN	111..150	CDD:283551	23/38 (61%)
TGIF2LX	NP_620410.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..58		15/71 (21%)
		Homeobox_KN	68..107	CDD:283551	23/38 (61%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	126..210		7/34 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152665
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D627308at33208
OrthoFinder	1	1.000	-	-		FOG0002434
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.810