Protein Alignment achi and Pbx4

DIOPT Version :10

• Sequence 1: NP_725183.1
• Gene: achi / 36373
• FlyBaseID: FBgn0033749
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001020125.1
• Gene: Pbx4 / 80720
• MGIID: 1931321
• Length: 378
• Species: Mus musculus
• Alignment Length: 260
• Identity: 59/260 - (22%)
• Similarity: 101/260 - (38%)
• Gaps: 74/260 - (28%)

  Fly    43 FHS-----DSSLDQDSLHADVIVEED--------QSTEHGANQVQNYHD-------------MMV 81
            :||     :.:..:.:.|...::.|.        :..||..|.:|:...             :|.
Mouse   143 YHSELEKYEQACREFTTHVTNLLREQSRVRPVSCREMEHMVNTIQSKFSAIQRQLKQSTCEAVMT 207

  Fly    82 DSEHHIDINGSLRKRRGNLPKTSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFIN 146
            .....:|    .|::|.|..|.:..:|..:.|.|..|.|||:..|..|:::..:||.||.|||.|
Mouse   208 LRSRFLD----ARRKRRNFSKQATDVLNEYFYSHLSNPYPSEETKEELARKGGITVSQVSNWFGN 268

  Fly   147 ARRRILPEMIRREGNDPLH------FTISRRGKKVSPNCSRSSALGANLTGPNP-AHGSPASEVV 204
            .|.|......:.:....::      .|.:||.:..| :|..:.:.|.  .||.| .:||..
Mouse   269 KRIRYKKNTGKFQEEATMYTGKASTVTKARRPRGQS-SCQSTPSPGP--CGPLPLTNGSDV---- 326

  Fly   205 VGATEEVDGAGEIHEGIANVLT-NFEQYVQGPNGQMVKMEPEYEDSVIYS-WQQAI---ANNPMG 264
                               ||| ....::|.|.|. |.::|     :::| ||:|.   |::|.|
Mouse   327 -------------------VLTLRTLAFLQPPTGG-VCLQP-----LVHSNWQRAAPQPASSPAG 366

  Fly   265  264
            Mouse   367  366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
achi	NP_725183.1	Homeobox_KN	112..150	CDD:428673	17/37 (46%)
Pbx4	NP_001020125.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24
		PBC	26..214	CDD:461052	9/70 (13%)
		PBC-A. /evidence=ECO:0000255|PROSITE-ProRule:PRU01322	29..107
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	100..125
		PBC-B. /evidence=ECO:0000255|PROSITE-ProRule:PRU01322	110..214		9/70 (13%)
		homeodomain	216..276	CDD:238039	23/59 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	291..320		8/31 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	355..378		4/12 (33%)