Protein Alignment achi and PBX4

DIOPT Version :10

• Sequence 1: NP_725183.1
• Gene: achi / 36373
• FlyBaseID: FBgn0033749
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_011526622.1
• Gene: PBX4 / 80714
• HGNCID: 13403
• Length: 391
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 55/242 - (22%)
• Similarity: 86/242 - (35%)
• Gaps: 69/242 - (28%)

  Fly    29 HVQASLLENEGRGRFHSDSSLDQ--DSLHADVIVEEDQSTEHGANQVQNYHDMMVDSEHHIDING 91
            || .:||:.:.|.|..|...:::  .::|......:.|..:.....|......::|:
Human   172 HV-TNLLQEQSRMRPVSPKEIERMVGAIHGKFSAIQMQLKQSTCEAVMTLRSRLLDA-------- 227

  Fly    92 SLRKRRGNLPKTSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPEM- 155
              |::|.|..|.:.::|..:.|.|..|.|||:..|..|:::..||:.||.|||.|.|.|....|
Human   228 --RRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKKNMG 290

  Fly   156 -------------------IRREGND---------------PL-----HFTISRRGKKVSP---- 177
                               :...||.               ||     .|...|....:.|
Human   291 KFQEEATIYTGKTAVDTTEVGVPGNHASCLSTPSSGSSGPFPLPSAGDAFLTLRTLASLQPPPGG 355

  Fly   178 NCSRSSALGA-NLTGPNPAHGSPASEVVVGATEEVDGAGEIHEGIAN 223
            .|.:|.|.|: ....|.||..|||.:           .|.|:...:|
Human   356 GCLQSQAQGSWQGATPQPATASPAGD-----------PGSINSSTSN 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
achi	NP_725183.1	Homeobox_KN	112..150	CDD:428673	17/37 (46%)
PBX4	XP_011526622.1	PBC	18..226	CDD:461052	10/54 (19%)
		homeodomain	228..289	CDD:238039	23/60 (38%)