Protein Alignment achi and IRX3

DIOPT Version :9

• Sequence 1: NP_001286352.1
• Gene: achi / 36373
• FlyBaseID: FBgn0033749
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_005256196.1
• Gene: IRX3 / 79191
• HGNCID: 14360
• Length: 529
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 68/296 - (22%)
• Similarity: 98/296 - (33%)
• Gaps: 104/296 - (35%)

  Fly    96 RRGNLPKTSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPEMIRREG 160
            |..|..:.|...||.||.|||.|.||:..||..|:....:|:.||..||.|||||
Human   130 RPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRR---------- 184

  Fly   161 NDPLHFTISRRGKKVSPNCSRSSALGANLTGPNPAHGSPASEVVVGATEEVDGAGEIH------- 218
                   :.:..|......||:...|       .|:||...|......|| ||..|:.
Human   185 -------LKKENKMTWAPRSRTDEEG-------NAYGSEREEEDEEEDEE-DGKRELELEEEELG 234

  Fly   219 --------EGIANVLTNFEQYVQGPNGQMVKMEPEY-------------------------EDSV 250
                    ||:|:  .:.::.:...|......|||.                         |||
Human   235 GEEEDTGGEGLAD--DDEDEEIDLENLDGAATEPELSLAGAARRDGDLGLGPISDSKNSDSEDS- 296

  Fly   251 IYSWQQAIANNPMGFQSL-------------------------HSSLQATMIDKIKNYQMRKAAA 290
                .:.:.:.|:...||                         .:...|:.:.|.|.:.:.:.|.
Human   297 ----SEGLEDRPLPVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIWSLAETAT 357

  Fly   291 IGGSAVGS-GGAGGSSSNSSPATSILPYSLFGQLPP 325
            ...:...| .||||    |.|..::.|.:|  ||.|
Human   358 SPDNPRRSPPGAGG----SPPGAAVAPSAL--QLSP 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
achi	NP_001286352.1	Homeobox_KN	111..150	CDD:283551	19/38 (50%)
IRX3	XP_005256196.1	Homeobox_KN	145..184	CDD:283551	19/38 (50%)
		IRO	344..359	CDD:214716	3/14 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900