DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment achi and Irx5

DIOPT Version :9

Sequence 1:	NP_001286352.1	Gene:	achi / 36373	FlyBaseID:	FBgn0033749	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_061296.1	Gene:	Irx5 / 54352	MGIID:	1859086	Length:	484	Species:	Mus musculus

Alignment Length:	334	Identity:	82/334 - (24%)
Similarity:	110/334 - (32%)	Gaps:	122/334 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 RGNLPKTSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRIL--------- 152
            |.|..:.:...||.||.|||.|.||:..||..|:....:|:.||..||.|||||:.
Mouse   116 RKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTP 180

  Fly   153 ---------PEMIRREGND------PLHFTISRRG-----------KKVSPNCSRSSALGANLTG 191
                     .|.|..|.||      |     ..:|           :|.:..|.|       |.|
Mouse   181 RNRSEDEEEEENIDLEKNDEDEPQKP-----EDKGDLEGPESGGAEQKATAGCER-------LQG 233

  Fly   192 PNPAHGSPASEVVVGATEEVDGAGEIHEGIANVLTN----FEQYVQGPNGQMVKME--PEYEDSV 250
            |.    |||.:...|:..:.|......||..:.|..    .|....||....:..:  |.|..||
Mouse   234 PL----SPAGKETEGSLSDSDFKESSSEGRHDELPRPPRAGESSPAGPATARLAEDAGPHYPASV 294

  Fly   251 IYSWQQAIANNPM---------GFQSLHS------------------SLQ--ATMIDKIKNYQMR 286
                 .|...:|.         |...:||                  ||.  ||..||:|:.
Mouse   295 -----PAPGPHPSAGELPPGSGGSSVIHSPPPPPPPPPAVLAKPKLWSLAEIATSSDKVKDG--- 351

  Fly   287 KAAAIGGSAVGS---------GG--AGGSSSNSSPATSILPYSLFGQLPPEFDDEEKPRPPKRVR 340
                 ||.:.||         ||  .|||.::.:||            |......:.|.|...|.
Mouse   352 -----GGGSEGSPCPPCPGPMGGQTLGGSRASPAPA------------PARSPSAQCPFPGGTVL 399

  Fly   341 TRTVAAKSP 349
            :|.:...:|
Mouse   400 SRPLYYTAP 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
achi	NP_001286352.1	Homeobox_KN	111..150	CDD:283551	19/38 (50%)
Irx5	NP_061296.1	Homeobox_KN	130..169	CDD:283551	19/38 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	176..393		52/257 (20%)
		IRO	328..345	CDD:214716	4/16 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	424..443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900