Protein Alignment achi and PBX1

DIOPT Version :10

• Sequence 1: NP_725183.1
• Gene: achi / 36373
• FlyBaseID: FBgn0033749
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_047277739.1
• Gene: PBX1 / 5087
• HGNCID: 8632
• Length: 486
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 65/280 - (23%)
• Similarity: 117/280 - (41%)
• Gaps: 69/280 - (24%)

  Fly    29 HVQASLLENEGRGRFHSDSSLDQ--DSLH---ADVIVEEDQSTEHGANQVQNYHDMMVDSEHHID 88
            ||. :||..:.|.|..|...:::  ..:|   :.:.::..|||         ...:|:.....:|
Human   234 HVM-NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQST---------CEAVMILRSRFLD 288

  Fly    89 INGSLRKRRGNLPKTSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILP 153
                .|::|.|..|.:.:||..:.|.|..|.|||:..|..|:::..:||.||.|||.|.|
Human   289 ----ARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKR----- 344

  Fly   154 EMIRREGNDPLHFTISRRGKKVSPNCSRSSALGANLTGPNPAHG----SPASEVVVGATE--EVD 212
              ||.:.|      |.:..::.:...::::....|::    |||    ||::....|::.  .:.
Human   345 --IRYKKN------IGKFQEEANIYAAKTAVTATNVS----AHGSQANSPSTPNSAGSSSSFNMS 397

  Fly   213 GAGEIHEGIANVLTNFEQYVQ-GPNGQ--------MVKMEPEYED----SVIYS---------WQ 255
            .:|::...:.::..:..|..| |.|.|        ::.....|.|    |.:||         ||
Human   398 NSGDLFMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQ 462

  Fly   256 QA-----IANNPMGFQSLHS 270
            .|     :.:...|..|:||
Human   463 DATTPSSVTSPTEGPGSVHS 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
achi	NP_725183.1	Homeobox_KN	112..150	CDD:428673	17/37 (46%)
PBX1	XP_047277739.1	PBC	42..288	CDD:461052	12/63 (19%)
		homeodomain	290..350	CDD:238039	25/66 (38%)