Protein Alignment achi and IRX4

DIOPT Version :10

• Sequence 1: NP_725183.1
• Gene: achi / 36373
• FlyBaseID: FBgn0033749
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001265562.1
• Gene: IRX4 / 50805
• HGNCID: 6129
• Length: 545
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 72/299 - (24%)
• Similarity: 103/299 - (34%)
• Gaps: 82/299 - (27%)

  Fly    87 IDINGSLRK------------RRGNLPKTSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQ 139
            :|::|..|.            ||.|..:.:...||.||.|||.|.||:..||..|:....:|:.|
Human   150 LDLSGLGRSPGSLYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQ 214

  Fly   140 VCNWFINARRRILPEMIRREGNDPLHFTISRRGKKVSPNCSRSSALGANLTGPNPAHGSPASEVV 204
            |..||.|||||     :::|..    .|...|.|     |:...              .|.:|
Human   215 VSTWFANARRR-----LKKENK----MTWPPRNK-----CADEK--------------RPYAE-- 249

  Fly   205 VGATEEVDGAGEIHEGIANVLTNFEQYVQGPNGQMV-KMEPEYEDSVIYSWQQAIANNPM----- 263
              ..||..|..|..|         |......|.:.| |.|.|.|.|.:..:....|..|.
Human   250 --GEEEEGGEEEARE---------EPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKP 303

  Fly   264 GFQSLHSSLQATMIDKIKNYQMRKAAAIGGSAVGSGGAGGSSSNSSPATSILPYSLFGQLP---- 324
            .|.||...|:  .:....:..:::|:.....::.:||......:...|.|.|..:..|..|
Human   304 PFHSLDGGLE--RVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGA 366

  Fly   325 ---PEFDD--------------EEKPRPPKRVRTRTVAA 346
               |:..:              |.|||......|.|.||
Human   367 EGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAAA 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
achi	NP_725183.1	Homeobox_KN	112..150	CDD:428673	18/37 (49%)
IRX4	NP_001265562.1	Homeobox_KN	187..225	CDD:428673	18/37 (49%)