DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment achi and exd

DIOPT Version :9

Sequence 1:	NP_001286352.1	Gene:	achi / 36373	FlyBaseID:	FBgn0033749	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001259592.1	Gene:	exd / 32567	FlyBaseID:	FBgn0000611	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	183	Identity:	46/183 - (25%)
Similarity:	72/183 - (39%)	Gaps:	51/183 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 RKRRGNLPKTSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPEMIRR 158
            |::|.|..|.:.:||..:.|.|..|.|||:..|..|:::..:||.||.|||.|.|       ||.
  Fly   239 RRKRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKR-------IRY 296

  Fly   159 EGNDPLHFTISRRGKKVSPNCSRSSALGA---NLTGPNPAHGSPASEVVVGATEEVDGAGEIHEG 220
            :.|      |.:..::.:...::.:| ||   ::.||.....:|    ::......|..|
  Fly   297 KKN------IGKAQEEANLYAAKKAA-GASPYSMAGPPSGTTTP----MMSPAPPQDSMG----- 345

  Fly   221 IANVLTNFEQYVQGPNGQMVKMEPEYEDSVIYSWQQAIANNPMGFQ-SLHSSL 272
                      |..|..|              |..||...|:..|:. :||..|
  Fly   346 ----------YPMGSGG--------------YDQQQPYDNSMGGYDPNLHQDL 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
achi	NP_001286352.1	Homeobox_KN	111..150	CDD:283551	17/38 (45%)
exd	NP_001259592.1	PBC	41..237	CDD:397732
exd	NP_001259592.1	homeodomain	239..299	CDD:238039	25/66 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457279
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840