DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment achi and irx-1

DIOPT Version :9

Sequence 1:	NP_001286352.1	Gene:	achi / 36373	FlyBaseID:	FBgn0033749	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_492533.2	Gene:	irx-1 / 172789	WormBaseID:	WBGene00007984	Length:	377	Species:	Caenorhabditis elegans

Alignment Length:	210	Identity:	55/210 - (26%)
Similarity:	85/210 - (40%)	Gaps:	41/210 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 GRFHSDSSLDQD-SLHADVIVEEDQSTEHGANQVQNY-HDMMVDSEHHIDING------------ 91
            |:||...::.|. :..|.......|:|..|...|..: |.:..|.:..:.:.|
Worm    41 GQFHFHPAMAQVLAAQAQAAAAAQQATLAGFPGVPMFPHGIPADLKPEMLLGGGPGPMPMFFSDA 105

  Fly    92 ----------SLRKRRGNLPKTSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFIN 146
                      .::||  |..:.:...||.||:.||.|.|||.|:|..|:....:|:.||..||.|
Worm   106 HRLYHPYGLDGIKKR--NATREATAPLKDWLHSHRKNPYPSKADKVMLAVGTGMTLTQVSTWFAN 168

  Fly   147 ARRRI--------LPEMIRREG----NDPLHFTISRRGKKVSPNCSR--SSALG-ANLTGPNPAH 196
            ||||:        .|:..|.:|    .|.....::|.....|.|..|  .|..| .:|..|.|:.
Worm   169 ARRRLKKENKMTWSPQNRRGDGCDDDEDDDDDDMNRPSSSTSINSERKGESLFGKPHLASPTPSG 233

  Fly   197 GSPASEVVVGATEEV 211
            ||..|:.:....:|:
Worm   234 GSGGSDELTTPKKEL 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
achi	NP_001286352.1	Homeobox_KN	111..150	CDD:283551	19/38 (50%)
irx-1	NP_492533.2	Homeobox_KN	133..172	CDD:283551	19/38 (50%)
irx-1	NP_492533.2	IRO	259..>273	CDD:214716
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900