Protein Alignment achi and Irx2

DIOPT Version :10

• Sequence 1: NP_725183.1
• Gene: achi / 36373
• FlyBaseID: FBgn0033749
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_034704.1
• Gene: Irx2 / 16372
• MGIID: 1197526
• Length: 474
• Species: Mus musculus
• Alignment Length: 269
• Identity: 66/269 - (24%)
• Similarity: 100/269 - (37%)
• Gaps: 57/269 - (21%)

  Fly    97 RGNLPKTSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPE------- 154
            |.|..:.:...||.||.|||.|.||:..||..|:....:|:.||..||.|||||:..|
Mouse   119 RKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAP 183

  Fly   155 MIRREGNDPLHFTISRRGKKVSPNCSRSSALGANLTGPNPAHGSPASEVVVGATEEVDG------ 213
            ..:.|..|......||..::.|......:...|...|.: .|....::....|  |.||
Mouse   184 RNKSEDEDEDEGDASRSKEESSDKAQDGTETSAEDEGIS-LHVDSLTDHSCSA--ESDGEKLPCR 245

  Fly   214 AGE-IHEGIANVLTNFEQYVQGPNGQMVKMEPEYEDSV--IYSWQQAIANNPMGFQSLHSSLQAT 275
            ||: :.|..:.....||.         ::.|.:.||..  ..:..:.:.::|:      :.::|.
Mouse   246 AGDALCESGSECKDKFED---------LEDEEDEEDECERDLAPPKPVTSSPL------TGVEAP 295

  Fly   276 MIDKIKNYQMRKAAAIGGSAVGSGGAGGSSSNSSPATSILPYSLFGQLPPEFDDEEKPRPPKRVR 340
            ::....     :||..|    ||||.....|.:||          |..||    ..||:......
Mouse   296 LLSPAP-----EAAPRG----GSGGKTPLGSRTSP----------GAPPP----ASKPKLWSLAE 337

  Fly   341 TRTVAAKSP 349
            ..|...|.|
Mouse   338 IATSDLKQP 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
achi	NP_725183.1	Homeobox_KN	112..150	CDD:428673	18/37 (49%)
Irx2	NP_034704.1	COG5576	<115..217	CDD:227863	31/97 (32%)
		Homeobox_KN	134..172	CDD:428673	18/37 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	177..220		6/42 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..373		24/123 (20%)
		IRO	325..342	CDD:214716	5/20 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	420..461