Protein Alignment vis and TGIF2LX

DIOPT Version :10

• Sequence 1: NP_788337.1
• Gene: vis / 36372
• FlyBaseID: FBgn0033748
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_620410.3
• Gene: TGIF2LX / 90316
• HGNCID: 18570
• Length: 241
• Species: Homo sapiens
• Alignment Length: 162
• Identity: 64/162 - (39%)
• Similarity: 90/162 - (55%)
• Gaps: 31/162 - (19%)

  Fly    76 DMMVDSEHHVDINGSL------RKRRGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLT 134
            |..:.|.::.|....|      :||:||||..|||||:.|:|:||:.||||:.||..||::.||:
Human    29 DTSIMSRNNADTGRVLALPEHKKKRKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLS 93

  Fly   135 VLQVCNWFINARRRILPEMIRREGNDPL--HFTISRRGKKV----VGATEEVDGAGEIHEGIANV 193
            :||:.||||||||||||:|:::..|||:  |.|    ||..    :.:||....|.....|..|
Human    94 LLQISNWFINARRRILPDMLQQRRNDPIIGHKT----GKDAHATHLQSTEASVPAKSGPSGPDN- 153

  Fly   194 LTNFEQYVQG------PNGQMVK-MEPEYEDS 218
                   ||.      |.|||.: .:|:.|.:
Human   154 -------VQSLPLWPLPKGQMSREKQPDPESA 178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vis	NP_788337.1	Homeobox_KN	110..148	CDD:428673	22/37 (59%)
TGIF2LX	NP_620410.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		8/28 (29%)
		Homeobox_KN	69..107	CDD:428673	22/37 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..210		16/65 (25%)