DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vis and pknox1.1

DIOPT Version :9

Sequence 1:	NP_788337.1	Gene:	vis / 36372	FlyBaseID:	FBgn0033748	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_571966.3	Gene:	pknox1.1 / 798151	ZFINID:	ZDB-GENE-020122-5	Length:	433	Species:	Danio rerio

Alignment Length:	233	Identity:	63/233 - (27%)
Similarity:	106/233 - (45%)	Gaps:	60/233 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 GANQVQNYHDMMVDSEHHVDINGSL----------RKRRGNLPKSSVKILKRWLYEHRYNAYPSD 121
            ||..:||       |:..:.:|..|          :.:||.|||.:..:::.||::|..:.||::
Zfish   239 GALHIQN-------SQLQLQLNQDLSFFGGDDSSPKNKRGVLPKQATNVMRSWLFQHIAHPYPTE 296

  Fly   122 AEKFTLSQEANLTVLQVCNWFINARRRILPEMIRREGNDPLHFTISRRGKKVVGATEEVDGAGEI 186
            .||..::.:.|||:|||.|||||||||||..|:  :.|.    |.:.:.||.|..:.      .:
Zfish   297 EEKKQIATQTNLTLLQVNNWFINARRRILQPML--DANS----TEASKSKKKVAQSR------PL 349

  Fly   187 H----EGIANVLTNFEQYVQGPNGQMVKMEPEYEDSVIYSWQQAIANNPMGFQSLHSSLQATMID 247
            |    :.||:  |..:|.:..|:|.:|                .:..|..|||:| ||..||:
Zfish   350 HRFWSDSIAS--TGSQQQLTMPDGSLV----------------TVGMNVDGFQAL-SSDGATL-- 393

  Fly   248 KIKNYQMRKAAAIGGSAVGSGGAGGSSSNSSPATSILP 285
                  ..:...:|..:.......|:..::..:|:.:|
Zfish   394 ------AMQQVLMGNHSEDETDESGNEDDTDMSTANMP 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vis	NP_788337.1	Homeobox_KN	109..148	CDD:283551	20/38 (53%)
pknox1.1	NP_571966.3	Meis_PKNOX_N	82..166	CDD:293102
pknox1.1	NP_571966.3	Homeobox_KN	284..323	CDD:283551	20/38 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587156
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740