Protein Alignment vis and IRX3

DIOPT Version :9

• Sequence 1: NP_788337.1
• Gene: vis / 36372
• FlyBaseID: FBgn0033748
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_005256196.1
• Gene: IRX3 / 79191
• HGNCID: 14360
• Length: 529
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 74/363 - (20%)
• Similarity: 101/363 - (27%)
• Gaps: 150/363 - (41%)

  Fly    94 RRGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPE----MI 154
            |..|..:.|...||.||.|||.|.||:..||..|:....:|:.||..||.|||||:..|    ..
Human   130 RPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWA 194

  Fly   155 RREGNDPLHFTISRRGKKVVGATEEVDGAGEIHEGIANVLTNFEQYVQGPNGQMVKMEPEYEDSV 219
            .|...|       ..|.......||.|...:..:|                    |.|.|.|:.
Human   195 PRSRTD-------EEGNAYGSEREEEDEEEDEEDG--------------------KRELELEEE- 231

  Fly   220 IYSWQQAIANNPMGFQSLHSSLQATMIDKIKNYQMRKAAAIGGSAVGSGGAGGSSSNSSPATSIL 284
                                                   .:||....:||.|
Human   232 ---------------------------------------ELGGEEEDTGGEG------------- 244

  Fly   285 PYSLFGQLPPEFDDEEKPRPPKRVRTRTVAAKSPRENAKQAKQKTGNKQETMYCYKDSYGGIVVS 349
                   |..:.:|||..     :.....||..|..:...|.::.|:.         ..|.|..|
Human   245 -------LADDDEDEEID-----LENLDGAATEPELSLAGAARRDGDL---------GLGPISDS 288

  Fly   350 PRSEGEESAQGYES-------------------------------CGPNSEEEVRFETSHDWQSV 383
            ..|:.|:|::|.|.                               |.|........:....|
Human   289 KNSDSEDSSEGLEDRPLPVLSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIW--- 350

  Fly   384 IKTVFGTEEVSTSAGN----NPGTSGSK--ASVQNTAI 415
                 ...|.:||..|    .||..||.  |:|..:|:
Human   351 -----SLAETATSPDNPRRSPPGAGGSPPGAAVAPSAL 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vis	NP_788337.1	Homeobox_KN	109..148	CDD:283551	19/38 (50%)
IRX3	XP_005256196.1	Homeobox_KN	145..184	CDD:283551	19/38 (50%)
		IRO	344..359	CDD:214716	3/22 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900