Protein Alignment vis and TGIF1

DIOPT Version :9

• Sequence 1: NP_788337.1
• Gene: vis / 36372
• FlyBaseID: FBgn0033748
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_775299.1
• Gene: TGIF1 / 7050
• HGNCID: 11776
• Length: 286
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 94/245 - (38%)
• Similarity: 131/245 - (53%)
• Gaps: 51/245 - (20%)

  Fly    28 AHVHASLLNNEGRDRFHSDSSLDQDSLHAVVGNDLSTEQGANQVQNYHDMMVDSEHHVDINGSLR 92
            |...:||.:::|........:.|:||:.  :..|||:..|:.:                     |
Human     9 ALARSSLTSSQGIVAASGSETEDEDSMD--IPLDLSSSAGSGK---------------------R 50

  Fly    93 KRRGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPEMIRRE 157
            :|||||||.||:||:.||||||||||||:.||..|||:.:|:.|||||||||||||:||:|:|::
Human    51 RRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKD 115

  Fly   158 GNDPLHFTISRRGKKVVGATEEVDGAGEIHEGIANVL-----TNFEQYVQGPN---GQMVKMEPE 214
            |.||..|||||||.| :..|..|:..    .||.|.:     |.|.....|||   |:.:..:|.
Human   116 GKDPNQFTISRRGAK-ISETSSVESV----MGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKPS 175

  Fly   215 YEDSVI-------YSWQQAIANNPMGFQSLHSSL---QATMIDKI--KNY 252
            ...||:       ::...|:.:.|.   ||..|:   |.|.|.:|  ||:
Human   176 SPGSVLARPSVICHTTVTALKDVPF---SLCQSVGVGQNTDIQQIAAKNF 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vis	NP_788337.1	Homeobox_KN	109..148	CDD:283551	29/38 (76%)
TGIF1	NP_775299.1	Homeobox_KN	67..106	CDD:283551	29/38 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152671
Domainoid	1	1.000	73	1.000	Domainoid score	I9250
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1573375at2759
OrthoFinder	1	1.000	-	-		FOG0002434
OrthoInspector	1	1.000	-	-		mtm8506
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2315
SonicParanoid	1	1.000	-	-		X2583
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.830