Protein Alignment vis and Irx6

DIOPT Version :10

• Sequence 1: NP_788337.1
• Gene: vis / 36372
• FlyBaseID: FBgn0033748
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_071873.2
• Gene: Irx6 / 64379
• MGIID: 1927642
• Length: 439
• Species: Mus musculus
• Alignment Length: 331
• Identity: 79/331 - (23%)
• Similarity: 113/331 - (34%)
• Gaps: 94/331 - (28%)

  Fly    94 RRGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPEMIRREG 158
            ||.|..:.|...||.||:|||.|.||:..||..|:....:|:.||..||.|||||     :::|.
Mouse   146 RRKNATRESTSALKAWLHEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRR-----LKKEN 205

  Fly   159 NDPLHFTISRRGKKVVGATEEVDGAGEIHEGIANVLTNFEQYVQGPNG---------QMVKMEPE 214
            .    .|.:.:.|   |..|....:||...|..|..|......|...|         :..:.|.|
Mouse   206 K----MTWAPKNK---GGEERKADSGEDSLGCLNGDTKDATASQEARGLRLSDLEDLEEEEEEEE 263

  Fly   215 YEDSVIYSWQQAIANNPMGFQSLH---SSLQATMIDK------IKNYQMRKAAAIGGS---AVGS 267
            .|:....|..:.:|:.....|.|.   ::.|...::.      :..:...:|...|.:   ....
Mouse   264 AEEEAAVSAARRLADFQKSTQPLPAPCAAAQERCLESRECGLGLPRFSFTEAPQSGEADFITAEP 328

  Fly   268 GG---------------------AGGSSSNSSPATSILPYSLFGQLPPEFDDEE---KPRPPKRV 308
            ||                     |..|:..|:|:|           ||.....|   .||.|..:
Mouse   329 GGPTMILHYPSGHKPRIWSLAHTAAASAVESAPST-----------PPRAQSPECHMIPRQPSSI 382

  Fly   309 RTRTVAAKSPRENAKQAKQKTGNKQETMYCYKDSYGGIVVSPRSEGEESAQGYE-SCGP---NSE 369
            |...|...|..|....|.:..||...|:                      ||.. :|.|   ..|
Mouse   383 RRLLVPRDSEGEEDSPAAKAFGNSTFTL----------------------QGLPLNCAPYPRRRE 425

  Fly   370 EEVRFE 375
            .||||:
Mouse   426 PEVRFQ 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vis	NP_788337.1	Homeobox_KN	110..148	CDD:428673	18/37 (49%)
Irx6	NP_071873.2	COG5576	<142..232	CDD:227863	35/97 (36%)
		Homeobox_KN	162..200	CDD:428673	18/37 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	205..270		14/71 (20%)