DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment vis and Irx5

DIOPT Version :9

Sequence 1:NP_788337.1 Gene:vis / 36372 FlyBaseID:FBgn0033748 Length:524 Species:Drosophila melanogaster
Sequence 2:NP_061296.1 Gene:Irx5 / 54352 MGIID:1859086 Length:484 Species:Mus musculus


Alignment Length:318 Identity:75/318 - (23%)
Similarity:101/318 - (31%) Gaps:119/318 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    95 RGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRIL--------- 150
            |.|..:.:...||.||.|||.|.||:..||..|:....:|:.||..||.|||||:.         
Mouse   116 RKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTP 180

  Fly   151 ---------PEMIRREGNDP------------------------------LHFTISRRGKKVVGA 176
                     .|.|..|.||.                              |...:|..||:..|:
Mouse   181 RNRSEDEEEEENIDLEKNDEDEPQKPEDKGDLEGPESGGAEQKATAGCERLQGPLSPAGKETEGS 245

  Fly   177 TEEVDGAGEIHEGIANVLTN----FEQYVQGPNGQMVKME--PEYEDSVIYSWQQAIANNPM--- 232
            ..:.|......||..:.|..    .|....||....:..:  |.|..||     .|...:|.   
Mouse   246 LSDSDFKESSSEGRHDELPRPPRAGESSPAGPATARLAEDAGPHYPASV-----PAPGPHPSAGE 305

  Fly   233 ------GFQSLHS------------------SLQ--ATMIDKIKNYQMRKAAAIGGSAVGS---- 267
                  |...:||                  ||.  ||..||:|:.        ||.:.||    
Mouse   306 LPPGSGGSSVIHSPPPPPPPPPAVLAKPKLWSLAEIATSSDKVKDG--------GGGSEGSPCPP 362

  Fly   268 -----GG--AGGSSSNSSPATSILPYSLFGQLPPEFDDEEKPRPPKRVRTRTVAAKSP 318
                 ||  .|||.::.:||            |......:.|.|...|.:|.:...:|
Mouse   363 CPGPMGGQTLGGSRASPAPA------------PARSPSAQCPFPGGTVLSRPLYYTAP 408

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
visNP_788337.1 Homeobox_KN 109..148 CDD:283551 19/38 (50%)
Irx5NP_061296.1 Homeobox_KN 130..169 CDD:283551 19/38 (50%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 176..393 45/241 (19%)
IRO 328..345 CDD:214716 4/16 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 424..443
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0773
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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