Protein Alignment vis and PBX1

DIOPT Version :9

• Sequence 1: NP_788337.1
• Gene: vis / 36372
• FlyBaseID: FBgn0033748
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_005245285.1
• Gene: PBX1 / 5087
• HGNCID: 8632
• Length: 486
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 77/384 - (20%)
• Similarity: 125/384 - (32%)
• Gaps: 135/384 - (35%)

  Fly    29 HVHASLLNNEGRDRFHSDSSLDQDSLHAVVGNDLSTEQGANQVQNYHDMMVDSEHHVDINGSLRK 93
            || .:||..:.|.|..|...:::  :.:::....|:.|...:......:|:.....:|    .|:
Human   234 HV-MNLLREQSRTRPISPKEIER--MVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLD----ARR 291

  Fly    94 RRGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPEMIRREG 158
            :|.|..|.:.:||..:.|.|..|.|||:..|..|:::..:||.||.|||.|.|.|.
Human   292 KRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRY--------- 347

  Fly   159 NDPLHFTISRRGKKVVGATEEVDGAGEIHEGIANVLTNFEQYVQGPNGQMVKMEPEYEDSVIYSW 223
                        ||.:|..:                                     |::.||:.
Human   348 ------------KKNIGKFQ-------------------------------------EEANIYAA 363

  Fly   224 QQAIANNPMGFQSLHSSLQATMIDKIKNYQMRKAAAIGGSAVGSGGAGGSSSNSSPATSILPYSL 288
            :.|:.              ||.:                ||.||.....|:.||:.::|....|.
Human   364 KTAVT--------------ATNV----------------SAHGSQANSPSTPNSAGSSSSFNMSN 398

  Fly   289 FGQLPPEFDDEEKPRPPKRVRTRTVAAKSPRENAKQAKQKTGNKQ---ETMYCYKDSYGGIVVSP 350
            .|.|                   .::.:|...::.|..|...|.|   :|:.......||.
Human   399 SGDL-------------------FMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGY---- 440

  Fly   351 RSEGEESAQGYESCGPNSEEEVRFETSHDWQSVIKTVFGTEEVSTSAGNNPGTSGSKAS 409
             |:|..::|.|...|        ...:..||...     |....||....||:..|..|
Human   441 -SDGLAASQMYSPQG--------ISANGGWQDAT-----TPSSVTSPTEGPGSVHSDTS 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vis	NP_788337.1	Homeobox_KN	109..148	CDD:283551	17/38 (45%)
PBX1	XP_005245285.1	PBC	40..288	CDD:281746	10/56 (18%)
		homeodomain	290..350	CDD:238039	25/80 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152681
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840