Protein Alignment vis and Irx5

DIOPT Version :10

• Sequence 1: NP_788337.1
• Gene: vis / 36372
• FlyBaseID: FBgn0033748
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001025215.1
• Gene: Irx5 / 498918
• RGDID: 1565518
• Length: 484
• Species: Rattus norvegicus
• Alignment Length: 317
• Identity: 74/317 - (23%)
• Similarity: 102/317 - (32%)
• Gaps: 117/317 - (36%)

  Fly    95 RGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRIL--------- 150
            |.|..:.:...||.||.|||.|.||:..||..|:....:|:.||..||:|||||:.
  Rat   116 RKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFVNARRRLKKENKMTWTP 180

  Fly   151 ---------PEMIRREGNDP------------------------------LHFTISRRGKKVVGA 176
                     .|.|..|.||.                              |...:|..||:..|:
  Rat   181 RNRSEDEEEEENIDLEKNDEDEPQKPEDKGDLEGPEAGGTEQKAAAGCERLQGPLSPAGKETEGS 245

  Fly   177 TEEVDGAGEIHEGIANVLTN----FEQYVQGPNGQMVKME--PEYE------------------- 216
            ..:.|......||..:.|..    .|....||....:..:  |.|.
  Rat   246 LSDSDFKESPSEGRHDDLPRPPRAGEPSPAGPATARLAEDAGPHYPAGAPAPGPHPSAGELPPGS 310

  Fly   217 --DSVIYS------WQQAIANNPMGFQSLHSSLQ-ATMIDKIKNYQMRKAAAIGGSAVGS----- 267
              .|||:|      ...|:...|    .|.|..: ||..||:|:.        ||.:.||
  Rat   311 GGSSVIHSPPPPPPPPPAVLAKP----KLWSLAEIATSSDKVKDG--------GGGSEGSPCPPC 363

  Fly   268 ----GG--AGGSSSNSSPATSILPYSLFGQLPPEFDDEEKPRPPKRVRTRTVAAKSP 318
                ||  .|||.::.:||            |......:.|.|...|.:|.:...:|
  Rat   364 PGPIGGQTLGGSRASPAPA------------PARSPSAQCPFPGGTVLSRPLYYTAP 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vis	NP_788337.1	Homeobox_KN	110..148	CDD:428673	18/37 (49%)
Irx5	NP_001025215.1	Homeobox_KN	131..169	CDD:428673	18/37 (49%)
		PHA03247	<223..411	CDD:223021	44/210 (21%)