Protein Alignment vis and Irx3

DIOPT Version :10

• Sequence 1: NP_788337.1
• Gene: vis / 36372
• FlyBaseID: FBgn0033748
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_006255254.1
• Gene: Irx3 / 307721
• RGDID: 1307424
• Length: 522
• Species: Rattus norvegicus
• Alignment Length: 333
• Identity: 77/333 - (23%)
• Similarity: 100/333 - (30%)
• Gaps: 110/333 - (33%)

  Fly    94 RRGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPE----MI 154
            |..|..:.|...||.||.|||.|.||:..||..|:....:|:.||..||.|||||:..|    ..
  Rat   133 RPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWA 197

  Fly   155 RREGNDPLHFTISRRGKKVVGATEEVDGAGEIHEGIANVLTNFEQYVQGPNGQMVKMEPEYEDSV 219
            .|...|       ..|.......||.|...:..||                    |.|.|.|:.
  Rat   198 PRSRTD-------EEGNAYGSEREEEDEEEDEEEG--------------------KRELEMEEE- 234

  Fly   220 IYSWQQAIANNPMGFQSLHSSLQATMIDKIKNYQMRKAAA---IGGSAVGSGGAG---------G 272
                :.|......|.:.|....:...|| ::|.....|.:   :.|:|..:|..|         .
  Rat   235 ----ELAGEEEDTGGEGLADDDEDEEID-LENLDSAAAGSELTLAGTAHRNGDFGLGPISDCKNS 294

  Fly   273 SSSNSSPATSILPYSLFGQLPPEFDDEEKPRPPKRVRTRTVAAKSPRENAKQAKQKTGNKQETMY 337
            .|.:||.:....|.|:...         .|.||...|    |..||
  Rat   295 DSDDSSESLEERPLSVLSL---------APAPPPVAR----APASP------------------- 327

  Fly   338 CYKDSYGGIVVSPRSEGEESAQGYESCGPNSEEEVRFETSHDWQSVIKTVFGTEEVSTSAGN--- 399
                      .||.|       |.:.|.|........:....|        ...|.:||..|
  Rat   328 ----------PSPPS-------GLDPCAPAPAPSSTLQKPKIW--------SLAETATSPDNPRR 367

  Fly   400 -NPGTSGS 406
             .||..||
  Rat   368 SPPGAGGS 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vis	NP_788337.1	Homeobox_KN	110..148	CDD:428673	18/37 (49%)
Irx3	XP_006255254.1	Homeobox_KN	149..187	CDD:428673	18/37 (49%)
		IRO	345..362	CDD:214716	3/24 (13%)