DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vis and Irx1

DIOPT Version :9

Sequence 1:	NP_788337.1	Gene:	vis / 36372	FlyBaseID:	FBgn0033748	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001100801.1	Gene:	Irx1 / 306659	RGDID:	1309060	Length:	480	Species:	Rattus norvegicus

Alignment Length:	237	Identity:	62/237 - (26%)
Similarity:	90/237 - (37%)	Gaps:	54/237 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 RRGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPE------ 152
            |..|..:.|...||.||.|||.|.||:..||..|:....:|:.||..||.|||||:..|
  Rat   130 RPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWG 194

  Fly   153 MIRREGNDPLHFTISRRGKKVVGATEEVDGAGEIH-EGI------------ANVLTNFEQYVQGP 204
            ...::..|...|     |....|..|:.:...||. |.|            :|  .:.|..|:.|
  Rat   195 ARSKDQEDGALF-----GSDTEGDPEKAEDDEEIDLESIDIDQIDERDGDQSN--EDEEDKVEAP 252

  Fly   205 NGQMVKMEPEYEDSVIYSWQQAI--ANNPMGFQSLHSSLQATMIDKIKNYQMRKAAAIGGSAVGS 267
            ..::....|..:.|...|..:.:  .::|:|.....|...:|           :..:.|.:|||.
  Rat   253 RARVAPPAPARDQSSPLSAAETLKSQDSPLGLAKEVSEPGST-----------RLLSPGAAAVGL 306

  Fly   268 GGAGGSS----SNSSPATSILPYSLFGQLPPEFDDEEKPRPP 305
            .||..|.    |.:..|||           |:...:..|.||
  Rat   307 QGAPHSKPKIWSLAETATS-----------PDGAPKASPPPP 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vis	NP_788337.1	Homeobox_KN	109..148	CDD:283551	19/38 (50%)
Irx1	NP_001100801.1	Homeobox_KN	145..184	CDD:283551	19/38 (50%)
		SDA1	<194..>252	CDD:283052	12/64 (19%)
		IRO	309..326	CDD:214716	6/27 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810