Protein Alignment vis and Irx4

DIOPT Version :10

• Sequence 1: NP_788337.1
• Gene: vis / 36372
• FlyBaseID: FBgn0033748
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001100800.1
• Gene: Irx4 / 306655
• RGDID: 1309309
• Length: 515
• Species: Rattus norvegicus
• Alignment Length: 329
• Identity: 76/329 - (23%)
• Similarity: 117/329 - (35%)
• Gaps: 84/329 - (25%)

  Fly    94 RRGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPEMIRREG 158
            ||.|..:.:...||.||.|||.|.||:..||..|:....:|:.||..||.|||||     :::|.
  Rat   146 RRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRR-----LKKEN 205

  Fly   159 NDPLHFTISRRG-----KKVVGATEEVDGAGEIHEGIANVLTNFEQYVQGPNGQMVKMEPEYEDS 218
            .    .|...|.     |:..|..|| :.||| .|.....|.:.:.  :||.|   |.:.|.|.|
  Rat   206 K----MTWPPRNKCADEKRPYGEGEE-EEAGE-EESREEPLKSVKS--EGPAG---KEDKELELS 259

  Fly   219 VIYSWQQAIANNPMGFQSLHSSLQATMIDKIKNYQMRKAAAIGGSAVGSGGAGGSSSNSSPATSI 283
            .:..:      :|:..::....|:...                                .|..|:
  Rat   260 DLEDF------DPLDTETSECELKTPF--------------------------------QPLDSV 286

  Fly   284 LPYSLFGQLPPEFDDEEKPRPPKRVRTRTVAAKSPRENAKQAKQKTGNKQETMYCYKDSYGGIVV 348
            ..     ::||..|.      |...:...|..:.|...|..|.. .|:.:....|.:.:    ||
  Rat   287 PE-----RIPPSSDG------PGTGKEAPVTLRMPLGTADGAVM-DGDLERARNCLRST----VV 335

  Fly   349 SPRSEGEESAQGYES--------CGPNSEEEVR-FETSHDWQSVIKTVFGTEEVSTSAGNNPGTS 404
            :|.|..|...|..|:        ..||.|.:.| :..:|...:...|.....|..:......|::
  Rat   336 APDSGAEGGPQACEAKLTFAPAGAPPNLETKPRIWSLAHTATAAAATALSQTEFPSCMLKRQGST 400

  Fly   405 GSKA 408
            |:.|
  Rat   401 GASA 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vis	NP_788337.1	Homeobox_KN	110..148	CDD:428673	18/37 (49%)
Irx4	NP_001100800.1	Homeobox_KN	162..200	CDD:428673	18/37 (49%)