Protein Alignment vis and Pbx1

DIOPT Version :10

• Sequence 1: NP_788337.1
• Gene: vis / 36372
• FlyBaseID: FBgn0033748
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001128334.1
• Gene: Pbx1 / 304947
• RGDID: 1308213
• Length: 430
• Species: Rattus norvegicus
• Alignment Length: 384
• Identity: 77/384 - (20%)
• Similarity: 125/384 - (32%)
• Gaps: 135/384 - (35%)

  Fly    29 HVHASLLNNEGRDRFHSDSSLDQDSLHAVVGNDLSTEQGANQVQNYHDMMVDSEHHVDINGSLRK 93
            || .:||..:.|.|..|...:::  :.:::....|:.|...:......:|:.....:|    .|:
  Rat   178 HV-MNLLREQSRTRPISPKEIER--MVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLD----ARR 235

  Fly    94 RRGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPEMIRREG 158
            :|.|..|.:.:||..:.|.|..|.|||:..|..|:::..:||.||.|||.|.|.|.
  Rat   236 KRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRY--------- 291

  Fly   159 NDPLHFTISRRGKKVVGATEEVDGAGEIHEGIANVLTNFEQYVQGPNGQMVKMEPEYEDSVIYSW 223
                        ||.:|..:                                     |::.||:.
  Rat   292 ------------KKNIGKFQ-------------------------------------EEANIYAA 307

  Fly   224 QQAIANNPMGFQSLHSSLQATMIDKIKNYQMRKAAAIGGSAVGSGGAGGSSSNSSPATSILPYSL 288
            :.|:.              ||.:                ||.||.....|:.||:.::|....|.
  Rat   308 KTAVT--------------ATNV----------------SAHGSQANSPSTPNSAGSSSSFNMSN 342

  Fly   289 FGQLPPEFDDEEKPRPPKRVRTRTVAAKSPRENAKQAKQKTGNKQ---ETMYCYKDSYGGIVVSP 350
            .|.|                   .::.:|...::.|..|...|.|   :|:.......||.
  Rat   343 SGDL-------------------FMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGY---- 384

  Fly   351 RSEGEESAQGYESCGPNSEEEVRFETSHDWQSVIKTVFGTEEVSTSAGNNPGTSGSKAS 409
             |:|..::|.|...|        ...:..||...     |....||....||:..|..|
  Rat   385 -SDGLAASQMYSPQG--------ISANGGWQDAT-----TPSSVTSPTEGPGSVHSDTS 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vis	NP_788337.1	Homeobox_KN	110..148	CDD:428673	17/37 (46%)
Pbx1	NP_001128334.1	PBC	42..232	CDD:461052	10/56 (18%)
		homeodomain	234..294	CDD:238039	25/80 (31%)