DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vis and meis2a

DIOPT Version :9

Sequence 1:	NP_788337.1	Gene:	vis / 36372	FlyBaseID:	FBgn0033748	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	XP_009291615.1	Gene:	meis2a / 170454	ZFINID:	ZDB-GENE-020122-2	Length:	409	Species:	Danio rerio

Alignment Length:	196	Identity:	59/196 - (30%)
Similarity:	88/196 - (44%)	Gaps:	38/196 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 NIKDLMHEAHVHASLLNNEGRDRFHSDSSLDQDSLH------------AVVGNDLSTEQGANQVQ 72
            |:.|.|....:.:..|.|....|.|.|::    |.|            |....|.|:|||.....
Zfish   205 NLADHMGNGWIRSDRLQNPASWRDHDDAT----STHSAGTPGPSSGGLASQSGDNSSEQGDGLDN 265

  Fly    73 NYHDMMVDSEHHVDINGSLRKRRGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQ 137
            :........:...|.:...:|:||..||.:..|::.||::|..:.|||:.:|..|:|:..||:||
Zfish   266 SVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQ 330

  Fly   138 VCNWFINARRRILPEMIRREGN-----DPLHFTISRRGKKVVGATEEVDGA--------GEIHEG 189
            |.||||||||||:..||.:...     ||   ::|:      ||....:|.        |:.|.|
Zfish   331 VNNWFINARRRIVQPMIDQSNRAGFLLDP---SVSQ------GAAYSPEGQPMGSFVLDGQQHMG 386

  Fly   190 I 190
            |
Zfish   387 I 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vis	NP_788337.1	Homeobox_KN	109..148	CDD:283551	21/38 (55%)
meis2a	XP_009291615.1	Meis_PKNOX_N	106..189	CDD:293102
meis2a	XP_009291615.1	Homeobox_KN	302..341	CDD:283551	21/38 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587152
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840