Protein Alignment vis and Irx3

DIOPT Version :10

• Sequence 1: NP_788337.1
• Gene: vis / 36372
• FlyBaseID: FBgn0033748
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001240751.1
• Gene: Irx3 / 16373
• MGIID: 1197522
• Length: 522
• Species: Mus musculus
• Alignment Length: 264
• Identity: 66/264 - (25%)
• Similarity: 92/264 - (34%)
• Gaps: 60/264 - (22%)

  Fly    94 RRGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPE------ 152
            |..|..:.|...||.||.|||.|.||:..||..|:....:|:.||..||.|||||:..|
Mouse   133 RPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWA 197

  Fly   153 ---MIRREGNDPLHFTISRRGKKVVGATEEVDGAGEIHEGIANVLTNFEQYVQGPNGQMVKMEPE 214
               ....|||             ..|:..|.:...|..|.....|...|:.:.|          |
Mouse   198 PRSRTDEEGN-------------AYGSEREEEDEEEDEEESKRELEMEEEELAG----------E 239

  Fly   215 YEDSVIYSWQQAIANNPMGFQSLHSSLQATMIDKIKNYQMRKAAA---IGGSAVGSGGAG----- 271
            .||:              |.:.|....:...|| ::|.....|.:   :.|:|..:|..|
Mouse   240 EEDT--------------GGEGLADDDEDEEID-LENLDSAAAGSELTLAGAAHRNGDFGLGPIS 289

  Fly   272 ----GSSSNSSPATSILPYSLFGQLPPEFDDEEKP-RPPKRVRTRTVAAKSPRENAKQAKQKTGN 331
                ..|.:||......|.|:....||.......| .||....:....|.:|..::...|.|..:
Mouse   290 DCKTSDSDDSSEGLEDRPLSVLSLAPPPPPVARAPASPPSPPSSLDPCAPAPAPSSALQKPKIWS 354

  Fly   332 KQET 335
            ..||
Mouse   355 LAET 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vis	NP_788337.1	Homeobox_KN	110..148	CDD:428673	18/37 (49%)
Irx3	NP_001240751.1	Homeobox_KN	149..187	CDD:428673	18/37 (49%)
		IRO	345..362	CDD:214716	4/14 (29%)