Protein Alignment vis and Irx1

DIOPT Version :10

• Sequence 1: NP_788337.1
• Gene: vis / 36372
• FlyBaseID: FBgn0033748
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_034703.2
• Gene: Irx1 / 16371
• MGIID: 1197515
• Length: 480
• Species: Mus musculus
• Alignment Length: 237
• Identity: 58/237 - (24%)
• Similarity: 89/237 - (37%)
• Gaps: 54/237 - (22%)

  Fly    94 RRGNLPKSSVKILKRWLYEHRYNAYPSDAEKFTLSQEANLTVLQVCNWFINARRRILPE------ 152
            |..|..:.|...||.||.|||.|.||:..||..|:....:|:.||..||.|||||:..|
Mouse   130 RPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWG 194

  Fly   153 MIRREGNDPLHFTISRRGKKVVGATEEVDGAGEIH-EGI------------ANVLTNFEQYVQGP 204
            ...::..|...|     |....|..|:.:...||. |.|            :|  .:.|...:.|
Mouse   195 ARSKDQEDGALF-----GSDTEGDPEKAEDDEEIDLESIDIDQIDERDGDQSN--EDEEDKAEAP 252

  Fly   205 NGQMVKMEPEYEDSVIYSWQQAI--ANNPMGFQSLHSSLQATMIDKIKNYQMRKAAAIGGSAVGS 267
            ..::.......:.|...|..:.:  .::|:|           ::.::......:..:.|.:|||.
Mouse   253 RARVAPPASARDQSSPLSAAETLKSQDSPLG-----------LVKEVSEPGSTRLLSPGAAAVGL 306

  Fly   268 GGAGGSS----SNSSPATSILPYSLFGQLPPEFDDEEKPRPP 305
            .||..|.    |.:..|||           |:...:..|.||
Mouse   307 QGAPHSKPKIWSLAETATS-----------PDGAPKASPPPP 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vis	NP_788337.1	Homeobox_KN	110..148	CDD:428673	18/37 (49%)
Irx1	NP_034703.2	Homeobox_KN	146..184	CDD:428673	18/37 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..285		16/112 (14%)
		DNA_pol_phi	<195..257	CDD:461488	12/68 (18%)
		IRO	309..326	CDD:214716	6/27 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	318..354		8/31 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	401..480