Protein Alignment Dh44-R2 and GLP2R

DIOPT Version :9

• Sequence 1: NP_610789.3
• Gene: Dh44-R2 / 36368
• FlyBaseID: FBgn0033744
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: XP_011522379.1
• Gene: GLP2R / 9340
• HGNCID: 4325
• Length: 578
• Species: Homo sapiens
• Alignment Length: 452
• Identity: 132/452 - (29%)
• Similarity: 204/452 - (45%)
• Gaps: 96/452 - (21%)

  Fly    47 SGGQLQNRTLQCQQQQQREEEQASLEALASGGKRILQCPSSFDSVLCWPRTNAGSLAV-----LP 106
            :|..|:..|.:..|.     :||.|..|......|. |..:||..:|||.::.|:::|     ||
Human    65 TGSLLEETTRKWAQY-----KQACLRDLLKEPSGIF-CNGTFDQYVCWPHSSPGNVSVPCPSYLP 123

  Fly   107 CFEE-----------FKG--------VHYDTTDNATRFCFPNGTW-------DHYSDYDRCHQNS 145
            .:.|           |.|        ...:::..|.|.|...|||       |.:.|...|.:|.
Human   124 WWSEDHQQIQGQLKLFSGKISGYKLQAKQESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENH 188

  Fly   146 GSIPVVPDFSPNVELPAII------YAGGYFLSFATLVVALIIFLSFKDLRCLRNTIHANLFLTY 204
                   .|..||:..|::      |..||..|..:|.:||.:.|..:.|.|.||.||.|||.::
Human   189 -------SFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASF 246

  Fly   205 I--TSALL-------------------WILTLFLQVITTESSQAGCITLVIMFQYFYLTNFFWMF 248
            |  |.|:|                   |:  .:|..::|     .|.::.::..||...|:.|:.
Human   247 ILRTLAVLVKDVVFYNSYSKRPDNENGWM--SYLSEMST-----SCRSVQVLLHYFVGANYLWLL 304

  Fly   249 VEGLYLYTLVVQTFSSDNISFIIYALIGWGCPAVCILVWSIAKAFAPHLENEHFNGLEIDCAWMR 313
            ||||||:||:..|...:...:..|.|:||..|.:.::.|..|:|   ||||       ..| |..
Human   305 VEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARA---HLEN-------TGC-WTT 358

  Fly   314 ESH--IDWIFKVPASLALLVNLVFLIRIMWVLITKLRSAHTLETRQY-YKASKALLVLIPLFGIT 375
            ..:  |.||.:.|..|.:.||....::|:.:||:||: ||.:..|.| |:.:|:.||||||.|:.
Human   359 NGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLK-AHQMCFRDYKYRLAKSTLVLIPLLGVH 422

  Fly   376 YLL---VLTGPEQGISRNLFEAIRAFLISTQGFFVALFYCFLNSEVRQTLRHGFTRWRESRN 434
            .:|   :.....:|.::.:...|:..|.|..||.|||.|.|.|.||:..||..:.|:..:|:
Human   423 EILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLARH 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R2	NP_610789.3	HRM	82..144	CDD:280888	22/92 (24%)
		7tm_2	159..407	CDD:278432	85/280 (30%)
GLP2R	XP_011522379.1	HRM	93..187	CDD:280888	23/94 (24%)
		7tm_2	200..457	CDD:278432	84/275 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810