Protein Alignment Dh44-R2 and VIPR2

DIOPT Version :9

• Sequence 1: NP_610789.3
• Gene: Dh44-R2 / 36368
• FlyBaseID: FBgn0033744
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: XP_005249618.1
• Gene: VIPR2 / 7434
• HGNCID: 12695
• Length: 463
• Species: Homo sapiens
• Alignment Length: 432
• Identity: 137/432 - (31%)
• Similarity: 197/432 - (45%)
• Gaps: 69/432 - (15%)

  Fly    64 REEEQASLEALASGGKRILQCPSSFDSVLCWPRTNAGSLAVLPCFEEFKGVHYDTTDNATRFCFP 128
            :|||....|.|.|..::...|...:|::.||...|.|....:||.:.|.. .|....|.::.|..
Human    57 QEEETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFSN-FYSKAGNISKNCTS 120

  Fly   129 NGTWDHYSDY-DRCHQNSGSIPVVPDFSPNVE---LPAIIYAGGYFLSFATLVVALIIFLSFKDL 189
            :|..:.:.|: |.|..:.      |:....:.   |...||..||.:|..:|....||...|:.|
Human   121 DGWSETFPDFVDACGYSD------PEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKL 179

  Fly   190 RCLRNTIHANLFLTYITSAL--------LWILTLFLQVITTESSQAGCITLVIMFQYFYLTNFFW 246
            .|.||.||.||||::|..|:        |:..:..|......||..||...::..||..:.||||
Human   180 HCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFW 244

  Fly   247 MFVEGLYLYTLVVQTFSSDNISFIIYALIGWGCPAVCILVWSIAKAFAPHLENEHFNGLEIDCAW 311
            :.||||||:||:|....... .|:.|.|||||.|.|||..|:.|:.:           ||....|
Human   245 LLVEGLYLHTLLVAMLPPRR-CFLAYLLIGWGLPTVCIGAWTAARLY-----------LEDTGCW 297

  Fly   312 MRESHID--WIFKVPASLALLVNLVFLIRIMWVLITKLRSAHT--LETRQYYKASKALLVLIPLF 372
            ....|..  |:.::|..::::||.|..|.|:.:|:.||.|...  .:..||.:.:|:.|:|||||
Human   298 DTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLF 362

  Fly   373 GITYLLVLTGPEQGISRN--LFEAIRAFLISTQGFFVALFYCFLNSEVRQTLRHGFTRWRE---- 431
            |:.|::....|....|:.  |||..   |.|.||..||:.||||||||:..|:.   :||.
Human   363 GVHYMVFAVFPISISSKYQILFELC---LGSFQGLVVAVLYCFLNSEVQCELKR---KWRSRCPT 421

  Fly   432 --------------SRN-------IHRNSSIKN-RSTEECVI 451
                          |||       .||.|..:: ..||..||
Human   422 PSASRDYRVCGSSFSRNGSEGALQFHRGSRAQSFLQTETSVI 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R2	NP_610789.3	HRM	82..144	CDD:280888	16/62 (26%)
		7tm_2	159..407	CDD:278432	91/264 (34%)
VIPR2	XP_005249618.1	HormR	77..143	CDD:214468	17/72 (24%)
		7tm_2	148..396	CDD:278432	91/262 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810