Protein Alignment Dh44-R2 and VIPR1

DIOPT Version :9

• Sequence 1: NP_610789.3
• Gene: Dh44-R2 / 36368
• FlyBaseID: FBgn0033744
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_004615.2
• Gene: VIPR1 / 7433
• HGNCID: 12694
• Length: 457
• Species: Homo sapiens
• Alignment Length: 468
• Identity: 150/468 - (32%)
• Similarity: 223/468 - (47%)
• Gaps: 75/468 - (16%)

  Fly    36 ASALIGAQQGSSGGQLQNRTLQCQQQQQREE------EQASLEALASGGKRILQCPSSFDSVLCW 94
            |.||..| .|.:|||......:|...|..|.      |:|.||      ...:.|...:|::.||
Human    16 AGALAWA-LGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLE------NETIGCSKMWDNLTCW 73

  Fly    95 PRTNAGSLAVLPC---FEEFKGVHYDTTDNATRFCFPNGTWDHYSDYDRCHQNSGSIPV---VPD 153
            |.|..|.:.||.|   |:.|..:.   ..|.:|.|...| |.|.        ..|..|:   :.|
Human    74 PATPRGQVVVLACPLIFKLFSSIQ---GRNVSRSCTDEG-WTHL--------EPGPYPIACGLDD 126

  Fly   154 FSPNVELPAIIYAG--------GYFLSFATLVVALIIFLSFKDLRCLRNTIHANLFLTYI-TSAL 209
            .:.:::....::.|        ||.||.|||:||..|...|:.|.|.||.||.:||:::| .:|.
Human   127 KAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAA 191

  Fly   210 LWI--LTLFLQVITTESSQ-----AGCITLVIMFQYFYLTNFFWMFVEGLYLYTLVVQTFSSDNI 267
            ::|  |.||   .:.||.|     .||...::.|||..:.||||:.|||||||||:..:|.|:..
Human   192 VFIKDLALF---DSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERK 253

  Fly   268 SFIIYALIGWGCPAVCILVWSIAKAFAPHLENEHFNGLEIDCAWMRESHIDWIFKVPASLALLVN 332
            .|..|.|||||.|:...:||:||:.        ||.  :..|.....|.:.||.|.|...::|||
Human   254 YFWGYILIGWGVPSTFTMVWTIARI--------HFE--DYGCWDTINSSLWWIIKGPILTSILVN 308

  Fly   333 LVFLIRIMWVLITKLR--SAHTLETRQYYKASKALLVLIPLFGITYLLVLTGPE--QGISRNLFE 393
            .:..|.|:.:|:.|||  .....::..|.:.:::.|:||||||:.|::....|:  :...:.:||
Human   309 FILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFE 373

  Fly   394 AIRAFLISTQGFFVALFYCFLNSEVRQTLRHGFTRWRESRNIHRNSSIKNRS--------TEECV 450
            .:   :.|.|||.||:.|||||.||:..||..:.||.....:..|...::.|        :.:..
Human   374 LV---VGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVS 435

  Fly   451 ICLRPSPHTRLGS 463
            :..|.||..|..|
Human   436 MLTRVSPGARRSS 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R2	NP_610789.3	HRM	82..144	CDD:280888	18/64 (28%)
		7tm_2	159..407	CDD:278432	94/267 (35%)
VIPR1	NP_004615.2	HormR	59..128	CDD:214468	21/80 (26%)
		7tm_2	139..384	CDD:278432	94/260 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X66
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810