Protein Alignment Dh44-R2 and PTH1R

DIOPT Version :9

• Sequence 1: NP_610789.3
• Gene: Dh44-R2 / 36368
• FlyBaseID: FBgn0033744
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: XP_011532269.1
• Gene: PTH1R / 5745
• HGNCID: 9608
• Length: 606
• Species: Homo sapiens
• Alignment Length: 498
• Identity: 142/498 - (28%)
• Similarity: 228/498 - (45%)
• Gaps: 87/498 - (17%)

  Fly     8 ALVDSLDDASQEDLAKVIANFSV-------DMLQRASALI-----------------GAQQGSSG 48
            ||||:.|..::|:...::.....       ::|||.:.|.                 |....|:.
Human    24 ALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPAQLTAIITTLVSPASIMESDKGWTSASTS 88

  Fly    49 GQLQNRTLQCQQQQQREEEQASLEALASGGKRILQCPSSFDSVLCWPRTNAGSLAVLPCFEEFKG 113
            |:.:......:...:.||::   ||......|...|...:|.:||||....|.:..:||.:..
Human    89 GKPRKDKASGKLYPESEEDK---EAPTGSRYRGRPCLPEWDHILCWPLGAPGEVVAVPCPDYI-- 148

  Fly   114 VHYDTT--DNATRFCFPNGTWDHYSDYDRCHQN-SGSIPVVPDFSPNVEL---PAIIYAGGYFLS 172
              ||..  .:|.|.|..||:|:....::|...| |..:..:.:.:...|:   ..:||..||.:|
Human   149 --YDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVS 211

  Fly   173 FATLVVALIIFLSFKDLRCLRNTIHANLFLTYITSALLWILTLF--------------------- 216
            .|:|.||::|...|:.|.|.||.||.:|||:::..|    :::|
Human   212 LASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRA----VSIFVKDAVLYSGATLDEAERLTEE 272

  Fly   217 -LQVI--------TTESSQAGCITLVIMFQYFYLTNFFWMFVEGLYLYTLVVQTFSSDNISFIIY 272
             |:.|        |..:..|||...|..|.||..||::|:.||||||::|:...|.|:......:
Human   273 ELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGF 337

  Fly   273 ALIGWGCPAVCILVWSIAKAFAPHLENEHFNGLEIDCAWMRESHIDWIFKVPASLALLVNLVFLI 337
            .:.|||.|||.:.||...:|   .|.|       ..|..:...:..||.:||...::::|.:..|
Human   338 TVFGWGLPAVFVAVWVSVRA---TLAN-------TGCWDLSSGNKKWIIQVPILASIVLNFILFI 392

  Fly   338 RIMWVLITKLR--SAHTLETRQYY-KASKALLVLIPLFGITYLLVLTGPEQGISRNLFEA---IR 396
            .|:.||.||||  :|...:|||.| |..|:.|||:||||:.|::.:..|...:|..|::.   ..
Human   393 NIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYE 457

  Fly   397 AFLISTQGFFVALFYCFLNSEVRQTLRHGFTRWRESRNIHRNS 439
            ....|.||||||:.|||.|.||:..::..::||..:.:..|.:
Human   458 MLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKA 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R2	NP_610789.3	HRM	82..144	CDD:280888	18/63 (29%)
		7tm_2	159..407	CDD:278432	92/286 (32%)
PTH1R	XP_011532269.1	HRM	118..186	CDD:280888	20/71 (28%)
		7tm_2	197..468	CDD:278432	91/284 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X66
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910