DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dh44-R2 and zgc:64002

DIOPT Version :9

Sequence 1:	NP_610789.3	Gene:	Dh44-R2 / 36368	FlyBaseID:	FBgn0033744	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001104716.2	Gene:	zgc:64002 / 393330	ZFINID:	ZDB-GENE-040426-1329	Length:	262	Species:	Danio rerio

Alignment Length:	227	Identity:	45/227 - (19%)
Similarity:	66/227 - (29%)	Gaps:	83/227 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 FQYFYLTNFFWMFVEGLYLYTLVVQTFSSDNISFIIYA-------------------LIGW---- 277
            |..|.|..|..:|..|.:....::...|..:|..:|.|                   :..|
Zfish    39 FLTFVLGVFSRLFSTGKHRGQRLIDVGSGPSIHCVISACAHYDEILLSDFSDNNRREIEKWLKNQ 103

  Fly   278 -GCPAVCILVWSIAKAFAPHLENEHFNGLE----------IDCAWMRESHIDWIFKVPASLALLV 331
             ||     |.||.........|.:..:.||          :.|....|:..|.:...||.
Zfish   104 EGC-----LDWSPILQHVSKTEGKRPSDLEATLKQRIKKVLKCDVRLENPFDPLTLEPAD----- 158

  Fly   332 NLVFLIRIMWVLITKLRSAHTLETRQYYKASKALLVLIPLFGITYLL----------VLTGPEQG 386
                      .:||.|......:..|.|:.:        |.|:|.||          ||:.....
Zfish   159 ----------CVITSLCLEAACKDMQIYRQA--------LHGLTKLLCPGGLFVMVGVLSETFYK 205

  Fly   387 ISRNLF-----------EAIRAFLISTQGFFV 407
            :...||           ||::.|..|.|.|.|
Zfish   206 VDEQLFSCLSLKQNDIEEALKGFGFSIQEFNV 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R2	NP_610789.3	HRM	82..144	CDD:280888
Dh44-R2	NP_610789.3	7tm_2	159..407	CDD:278432	44/225 (20%)
zgc:64002	NP_001104716.2	AdoMet_MTases	2..260	CDD:302624	45/227 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900