Protein Alignment Dh44-R2 and Fbxo46

DIOPT Version :10

• Sequence 1: NP_610789.3
• Gene: Dh44-R2 / 36368
• FlyBaseID: FBgn0033744
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_001020813.1
• Gene: Fbxo46 / 292686
• RGDID: 1308393
• Length: 603
• Species: Rattus norvegicus
• Alignment Length: 129
• Identity: 27/129 - (20%)
• Similarity: 39/129 - (30%)
• Gaps: 51/129 - (39%)

  Fly     4 DDLRALVDSLDDASQEDLAKVIANFSVDMLQRAS-----ALIGAQQGS----------SGGQLQN 53
            ||    ||.|..|....|.:..|..::....|.|     ..:.|:||.          |||...:
  Rat   165 DD----VDLLSVAEMVALVEQRAALALQSYPRPSTPAPVVFVSAEQGGPAKGLGSERRSGGGDCS 225

  Fly    54 RTLQ--CQQQQQRE------------------------------EEQASLEALASGGKRILQCP 85
            |..:  ...:.||:                              |.|:...:||:||.....||
  Rat   226 RVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISNVREPQSPDGSLANGGGGRPACP 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R2	NP_610789.3	HRM	82..144	CDD:397086	2/4 (50%)
		7tmB1_DH_R	158..428	CDD:320391
		TM helix 1	160..185	CDD:320391
		TM helix 2	194..216	CDD:320391
		TM helix 3	230..257	CDD:320391
		TM helix 4	269..289	CDD:320391
		TM helix 5	314..343	CDD:320391
		TM helix 6	357..384	CDD:320391
		TM helix 7	390..415	CDD:320391
Fbxo46	NP_001020813.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..54
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..163
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	235..301		10/55 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	332..359
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	396..442
		F-box_FBXO46	473..519	CDD:438948