Protein Alignment Dh44-R2 and GHRHR

DIOPT Version :9

• Sequence 1: NP_610789.3
• Gene: Dh44-R2 / 36368
• FlyBaseID: FBgn0033744
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_000814.2
• Gene: GHRHR / 2692
• HGNCID: 4266
• Length: 423
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 132/402 - (32%)
• Similarity: 181/402 - (45%)
• Gaps: 64/402 - (15%)

  Fly    62 QQREEEQASLEALASGGKRILQCPSSFDSVLCWPRTNAGSLAVLPCFEEFKGVHYDTTDNAT-RF 125
            |.||:|.|.|:|........|.||:::|.:||||...:|....|||.:.|.  |:.:...|. |.
Human    33 QLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS--HFSSESGAVKRD 95

  Fly   126 CFPNGTWDHYSDYDRCHQNSGSIPV---VPDFSPNVELPA----------IIYAGGYFLSFATLV 177
            |...|..:.:..|          ||   ||     :||.|          |||..|:.:|...|.
Human    96 CTITGWSEPFPPY----------PVACPVP-----LELLAEEESYFSTVKIIYTVGHSISIVALF 145

  Fly   178 VALIIFLSFKDLRCLRNTIHANLFLTYITSA---LLWILTLFLQVITTESSQAG--CITLVIMFQ 237
            ||:.|.::.:.|.|.||.:|..||.|:|..|   .|....||....|...|.:.  |...|....
Human   146 VAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASH 210

  Fly   238 YFYLTNFFWMFVEGLYLYTLVVQTFSSDNISFIIYALIGWGCPAVCILVWSIAK-AFAPHLENEH 301
            :..:|||.|:..|.:||..|:..|..|...:|....|.|||.|.:....|...| ||.
Human   211 FATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFE------- 268

  Fly   302 FNGLEIDCAWMRE--SHIDWIFKVPASLALLVNLVFLIRIMWVLITKLRSAH-TLETR-QYYKAS 362
                :|.| |..:  |...||.|.|..|::.||....:.|:.:|:.||..|. :|.|: ||::.|
Human   269 ----DIAC-WDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLS 328

  Fly   363 KALLVLIPLFGITYLLVLTGPEQ-GISRNLFEAIRAFLISTQGFFVALFYCFLNSEVRQTLR--- 423
            |:.|.|||||||.|::....|:. |:...|  .:...|.|.|||.||:.|||||.|||..:.
Human   329 KSTLFLIPLFGIHYIIFNFLPDNAGLGIRL--PLELGLGSFQGFIVAILYCFLNQEVRTEISRKW 391

  Fly   424 HG-----FTRWR 430
            ||     ...||
Human   392 HGHDPELLPAWR 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R2	NP_610789.3	HRM	82..144	CDD:280888	19/62 (31%)
		7tm_2	159..407	CDD:278432	88/268 (33%)
GHRHR	NP_000814.2	HRM	52..112	CDD:280888	21/71 (30%)
		7tm_2	126..372	CDD:278432	85/259 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X66
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810