Protein Alignment Dh44-R2 and Vipr1

DIOPT Version :10

• Sequence 1: NP_610789.3
• Gene: Dh44-R2 / 36368
• FlyBaseID: FBgn0033744
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_036817.1
• Gene: Vipr1 / 24875
• RGDID: 3961
• Length: 459
• Species: Rattus norvegicus
• Alignment Length: 462
• Identity: 153/462 - (33%)
• Similarity: 222/462 - (48%)
• Gaps: 82/462 - (17%)

  Fly    47 SGGQLQNRTLQCQQQQ----QREE--EQASLEALASGGKRILQCPSSFDSVLCWPRTNAGSLAVL 105
            :|.|..:...:|:..|    ||::  |:|.||...:|      |...:|::.|||.|..|...||
  Rat    26 AGSQAASPQHECEYLQLIEIQRQQCLEEAQLENETTG------CSKMWDNLTCWPTTPRGQAVVL 84

  Fly   106 PC---FEEFKGVH-YDTTDNATRFCFPNGTW---------------DHYSDYDRCHQNSGSIPVV 151
            .|   |:.|..:| |    |.:|.|...| |               |..|..|...|..
  Rat    85 DCPLIFQLFAPIHGY----NISRSCTEEG-WSQLEPGPYHIACGLNDRASSLDEQQQTK------ 138

  Fly   152 PDFSPNVELPAIIYAGGYFLSFATLVVALIIFLSFKDLRCLRNTIHANLFLTYI---TSALLWIL 213
              |...|:..   |..||.||.|:|:||:.|...|:.|.|.||.||.:||:::|   |:..:..:
  Rat   139 --FYNTVKTG---YTIGYSLSLASLLVAMAILSLFRKLHCTRNYIHMHLFMSFILRATAVFIKDM 198

  Fly   214 TLFLQVITTESSQA--GCITLVIMFQYFYLTNFFWMFVEGLYLYTLVVQTFSSDNISFIIYALIG 276
            .||........|:|  ||...|:.|||..:.||||:.|||||||||:..:|.|:...|..|.|||
  Rat   199 ALFNSGEIDHCSEASVGCKAAVVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIG 263

  Fly   277 WGCPAVCILVWSIAKAFAPHLENEHFNGLEIDCAW--MRESHIDWIFKVPASLALLVNLVFLIRI 339
            ||.|:|.|.:|::.:.:.     |.|.      .|  :..|.:.||.|.|..|::|||.|..|.|
  Rat   264 WGVPSVFITIWTVVRIYF-----EDFG------CWDTIINSSLWWIIKAPILLSILVNFVLFICI 317

  Fly   340 MWVLITKLR--SAHTLETRQYYKASKALLVLIPLFGITYLLVLTGPE--QGISRNLFEAIRAFLI 400
            :.:|:.|||  .....::..|.:.:|:.|:|||||||.|::....|:  :...:.:||.:   :.
  Rat   318 IRILVQKLRPPDIGKNDSSPYSRLAKSTLLLIPLFGIHYVMFAFFPDNFKAQVKMVFELV---VG 379

  Fly   401 STQGFFVALFYCFLNSEVRQTLRHGFTRWR-------ESRNIH--RNSSIKNRSTEECVICLRPS 456
            |.|||.||:.|||||.||:..||..:.||.       .|::.|  ..|:....||:..:: .|.|
  Rat   380 SFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWSSKSQHPWGGSNGATCSTQVSML-TRVS 443

  Fly   457 PHTRLGS 463
            |..|..|
  Rat   444 PSARRSS 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R2	NP_610789.3	HRM	82..144	CDD:397086	22/80 (28%)
		7tmB1_DH_R	158..428	CDD:320391	106/280 (38%)
		TM helix 1	160..185	CDD:320391	10/24 (42%)
		TM helix 2	194..216	CDD:320391	7/24 (29%)
		TM helix 3	230..257	CDD:320391	15/26 (58%)
		TM helix 4	269..289	CDD:320391	11/19 (58%)
		TM helix 5	314..343	CDD:320391	12/28 (43%)
		TM helix 6	357..384	CDD:320391	11/26 (42%)
		TM helix 7	390..415	CDD:320391	11/24 (46%)
Vipr1	NP_036817.1	HormR	59..130	CDD:214468	21/81 (26%)
		7tmB1_VIP-R1	140..407	CDD:320397	106/283 (37%)
		TM helix 1	142..167	CDD:320397	11/27 (41%)
		TM helix 2	176..198	CDD:320397	7/21 (33%)
		TM helix 3	217..244	CDD:320397	15/26 (58%)
		TM helix 4	256..276	CDD:320397	11/19 (58%)
		TM helix 5	292..321	CDD:320397	12/28 (43%)
		TM helix 6	337..364	CDD:320397	11/26 (42%)
		TM helix 7	369..394	CDD:320397	11/27 (41%)