Protein Alignment Dh44-R2 and vipr1

DIOPT Version :10

• Sequence 1: NP_610789.3
• Gene: Dh44-R2 / 36368
• FlyBaseID: FBgn0033744
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: XP_031759879.1
• Gene: vipr1 / 100497291
• XenbaseID: XB-GENE-5991267
• Length: 444
• Species: Xenopus tropicalis
• Alignment Length: 413
• Identity: 128/413 - (30%)
• Similarity: 204/413 - (49%)
• Gaps: 65/413 - (15%)

  Fly    82 LQCPSSFDSVLCWPRTNAGSLAVLPCFEEFKGVHYDTTDNATRFCFPNGTWDHY-------SDYD 139
            |.|.:|:|::.||...:.|.:.|:||.:.| |...:...|.:|.|..:|..|.:       ..:|
 Frog    51 LGCKASWDNITCWRSASVGEVVVMPCPDYF-GFFSNVQGNVSRNCTEHGWTDMFPAPYAIACGFD 114

  Fly   140 RCHQNSGSIPVVPDFSPNVELPAIIYAG---GYFLSFATLVVALIIFLSFKDLRCLRNTIHANLF 201
            ..:..:|          ..|..::|..|   |:.:|..:|..|:||...|:.|.|.||.||.:||
 Frog   115 TNNTTNG----------QTEFFSMIKTGYTIGHSVSLISLTAAMIILFFFRKLHCTRNYIHMHLF 169

  Fly   202 LTYITSALLWILTLFLQ-VITTESSQ--------AGCITLVIMFQYFYLTNFFWMFVEGLYLYTL 257
            :::|..|    :.:|:: ::..||.:        .||...::.|||..:.||||:.||||||:||
 Frog   170 MSFIMRA----IAVFVKDIVLFESGEFDHCFVGSVGCKAAMVFFQYCIMANFFWLLVEGLYLHTL 230

  Fly   258 VVQTFSSDNISFIIYALIGWGCPAVCILVWSIAKAFAPHLENEHFNGLEIDCAWMRESHIDWIFK 322
            :|.:|.|:...|..|.|||||.|.|.|..|::.:.        ||:  :..|....||...||.:
 Frog   231 LVISFFSEKKYFWWYILIGWGSPTVFITAWTVTRI--------HFD--DSGCWDTIESPFWWIIR 285

  Fly   323 VPASLALLVNLVFLIRIMWVLITKLRSAHT--LETRQYYKASKALLVLIPLFGITYLLVLTGPEQ 385
            .|..:::.||.:|.|.|:.:|:.||.|...  .|..||.:.:|:.|:||||||:.|::....|:.
 Frog   286 APILISISVNFIFFICIIRILVQKLHSPDVGRNENSQYTRLAKSTLLLIPLFGVHYIMFAFFPDN 350

  Fly   386 GISRNLFEA-----IRAFLISTQGFFVALFYCFLNSEVRQTLRHGFTRWRESRNI-----HRNSS 440
                  |:.     :...|.|.|||.||:.|||||.||:..|:..:.||...|.:     :.:.|
 Frog   351 ------FKVEIKLIVELVLGSFQGFVVAILYCFLNGEVQGELKRKWRRWHLERFLGSDMKYHHPS 409

  Fly   441 IKNRSTE---ECVICLRPSPHTR 460
            :.:..|.   :..:..:.||.||
 Frog   410 LGSNGTNFSTQISMLTKCSPKTR 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R2	NP_610789.3	HRM	82..144	CDD:397086	18/68 (26%)
		7tmB1_DH_R	158..428	CDD:320391	100/288 (35%)
		TM helix 1	160..185	CDD:320391	8/27 (30%)
		TM helix 2	194..216	CDD:320391	7/21 (33%)
		TM helix 3	230..257	CDD:320391	13/26 (50%)
		TM helix 4	269..289	CDD:320391	11/19 (58%)
		TM helix 5	314..343	CDD:320391	10/28 (36%)
		TM helix 6	357..384	CDD:320391	11/26 (42%)
		TM helix 7	390..415	CDD:320391	11/29 (38%)
vipr1	XP_031759879.1	HormR	50..120	CDD:214468	18/69 (26%)
		7tm_GPCRs	126..392	CDD:475119	99/285 (35%)
		TM helix 1	129..153	CDD:320397	8/23 (35%)
		TM helix 2	162..183	CDD:320397	8/24 (33%)
		TM helix 3	203..225	CDD:320397	9/21 (43%)
		TM helix 4	244..260	CDD:320397	9/15 (60%)
		TM helix 5	277..300	CDD:320397	8/22 (36%)
		TM helix 6	327..349	CDD:320397	9/21 (43%)
		TM helix 7	354..379	CDD:320397	10/24 (42%)