Protein Alignment Nepl10 and Nepl21

DIOPT Version :10

• Sequence 1: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Alignment Length: 769
• Identity: 156/769 - (20%)
• Similarity: 288/769 - (37%)
• Gaps: 228/769 - (29%)

  Fly     6 LLCSCLVALFIPIQAIVD-------------------INVATSNDIHNNLNRTTSPCTNFWNFAC 51
            |||.|:....  :.|:|.                   :..|.:.:|.:.:::...||.:|:.|:|
  Fly    12 LLCICIAGHV--LSAMVAAAPTSEEDLKQDTPYMKELLRQAKTAEIESFMDQKADPCNDFYAFSC 74

  Fly    52 GRF----SSASKYVDN---FERVEDQFATAMVEFMESHLGENDTLAPRLIKQMRQYYKAC----- 104
            |.:    |:.|..|..   ||.:.......:::.:.:....:||  |..|| ::.:|::|
  Fly    75 GNYKRINSALSMQVVTTGVFETLTKGLNRKILKMLNTPHDSHDT--PEDIK-VKHFYESCLQIKE 136

  Fly   105 -----KEDTRK----------LHGNPRPEELVNQWILHPKKFLV-YGLNGVF-IDERVDVAANDS 152
                 .|..::          |.|:...|:..: |:....:... ||:..:| |:...|:|:|..
  Fly   137 LNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFD-WLNTTARMAYRYGITPIFGIEVNKDLASNTR 200

  Fly   153 MRWVIQLRMPD-PAD-----------------RYSDRRVLQ-----LMRLYE---------EAWY 185
            .|  |.|...| |.:                 |.:.:|:||     .|.|.:         |...
  Fly   201 NR--IYLGQQDFPLEARSMYVDDATAVYRQKYRNNIQRILQRYLGVKMDLAKKTAKELIDFEVDL 263

  Fly   186 SMGVVKLVE-----KMHQL--QDKYRAEYPVVYTWSFSELRQEIPIPHSFFIELLGVNHTEELYH 243
            :.|:|...|     ::.||  .|:.:..|           ...:.|....|:. :|...::::|.
  Fly   264 AQGLVDESEGLDVGELTQLLTVDEIQRRY-----------SPTLDIDRLLFVS-MGERISDQIYE 316

  Fly   244 LT--FEVSDVEYLREC----------FRCLRDFASEPKDTYIRARQYVLVEESEPRERNPRSCIH 296
            ..  ::.:.||.::..          ||.:.:|...|.|:               .|:..::|:.
  Fly   317 YNNRYQQNLVEVIKRTPKRTVANYIFFRLIWEFVETPSDS---------------PEKQMKACVD 366

  Fly   297 HMRAYLPLGM-NYIYDRFIYQNREEDTSKVLEILSTLKAAFGQYLDA----NRLQLTPNQLAYVR 356
            ..:.|....: |..|.|:   |.|:.:.::..:...||:.|.:.|.:    |.::.....||  .
  Fly   367 LTKKYFAKNLDNMFYRRY---NNEKSSREIDNMWRQLKSTFNETLRSSPALNWIERPTRNLA--M 426

  Fly   357 AKLEGIQIKIGNLPEEKSPEFYNNHYGSANFSATNFLAN-----LLEAFALRTRLQNAGLLARNS 416
            |||:.:.:::.|..::.    :...:...|..:.:::.|     ||.|..:|..|...   |:..
  Fly   427 AKLQAMTLEVNNYADDN----FTEEFAELNLQSDDYVENVRYTSLLGAKQMREMLHKP---AKPF 484

  Fly   417 RVDLRHYYVNDNVRKARTSPFYENERNTITVPMEFLQWPLFDHREHTIFQHSL----LGAVLGHE 477
            ....:..|...|:.          ..|||.||:..|| |.:...:  ::.:::    |.:::|||
  Fly   485 EAGSQLSYTPANIL----------IENTIKVPVALLQ-PFYIWSD--VYPNAIMFGTLASLIGHE 536

  Fly   478 MNHAFEQEGILFDAAGNESPVGLEIRESKPFRDAIKCAEEQ------PFVSLK------ERLADL 530
            :.|.|:..|..||..|| |....:.:.|..|.....|..:|      ..:.||      |.:||.
  Fly   537 LIHGFDDSGRKFDEKGN-SKDWWDEKSSSNFLKRRDCFTKQYGRYVYDGIQLKESTAQSENIADN 600

  Fly   531 NGLQLAYDAFFGLAHDSRQFEYRPYAFEQ------------------EFTAPQLFHLSYAQFFCG 577
            .|::|||.|            ||.:...|                  .:||.|||.:|:||.:|.
  Fly   601 GGMRLAYTA------------YRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWCN 653

  Fly   578 SLPPVI--------AHDRDDERVNVSVGNLRQFAYDFNCET----SPSSVCEMW 619
            ...|.:        .|.....||..|:.|..:|:.:|||..    :||..|.::
  Fly   654 DAHPSVKALQVSTDQHMPGRFRVIGSLSNFEEFSKEFNCPAGSAMNPSEKCILY 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl10	NP_610787.1	GluZincin	41..608	CDD:472708	143/698 (20%)
Nepl21	NP_651646.2	M13	63..704	CDD:341056	147/711 (21%)