Protein Alignment Nepl10 and Nepl17

DIOPT Version :10

• Sequence 1: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Alignment Length: 716
• Identity: 139/716 - (19%)
• Similarity: 271/716 - (37%)
• Gaps: 193/716 - (26%)

  Fly    24 INVATSNDIHNNLNRTTSPCTNFWNFACGRF----SSASKYVDNFERVEDQFATAMVEFMESHLG 84
            :.:|.|.::.:.::.:.|||.:|:.:|||.:    ::.|:...|..::  .||. .:..:...|.
  Fly    39 MRIAKSAEMCSFMDTSVSPCDDFYGYACGNYATINAATSQKDTNIRQL--MFAN-YLRRVRQVLN 100

  Fly    85 ENDTLAPRLIK------QMRQYYKACKEDT--------------RKLHGNPRPE----------- 118
            |     ||:..      :::.:|::|.:..              |:..|.|..|
  Fly   101 E-----PRISTDRPMEVRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYVGFDA 160

  Fly   119 -ELVNQWILHPKKFLVYG-----------LNGVFIDERVDVAANDSM-----RWVIQLR------ 160
             |::.|.:....|..:.|           :..:.:.:|:|:|.:|..     ::.:::|
  Fly   161 IEMMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLGQRLDLAESDEFASLWKKYALKMRLRNLLG 225

  Fly   161 MPDPADRYSDRRVLQL-MRLYEEAW-YSMG----VVKLVEKMHQLQDKYRAEYPV------VYTW 213
            :.:...|.:...:::| :.|...|: :.|.    :::.:..:..:.|.|.   |:      |.:|
  Fly   226 LSEELARKTAEEIIELELELSRSAFDHRMNRDPRLMRHLTMLSNMSDAYG---PILNVTRFVTSW 287

  Fly   214 SFSELRQEI--PIPHSFF----IELLGVNHTEELYHLTFEVSDVEYLRECFRCLRDFASEPKDTY 272
            ..||....:  .:|...|    |.|...||....|.|:..::|.|..          |:|.:...
  Fly   288 LGSEYNLPVFESVPSYLFQVKKILLSTPNHVVANYMLSSLLTDFEIT----------ANEEQQKV 342

  Fly   273 IRARQYVLVEESEPRERNPRSCIHHMRAYLPLGMNYIYDRFIYQNREED----TSKVLEILSTLK 333
            |                    |...:....|    .:.|..:|.:.|:.    .:::..:...||
  Fly   343 I--------------------CHERITELFP----DVVDHMVYHSLEQQNPYIANEMRSLWVELK 383

  Fly   334 AAFGQYLDANRLQLTPNQL-AYVRAKLEGIQIKIG-----NLPEEKSPEFYNNHYGSANFSATNF 392
            ::|.:.|.:..::....|. ..:..||.|:..:|.     |..|:         :|....|:.::
  Fly   384 SSFREMLSSPDIEWLEKQTREELLEKLNGMSFEIAGGQAVNFEEQ---------FGDLVVSSADY 439

  Fly   393 LANLLEAFALRTRLQNAGLLARNSRVDLRHYYVNDNVRKARTSPFYENERNTITVPMEFLQWP-L 456
            ..|:.....::.|:....||..:|.|   :||     .....:|.||.|.|.:.:|:.::|.. |
  Fly   440 YGNIQRLLEVKARILRTDLLRESSSV---YYY-----HGVTATPIYETETNLVVLPVSYMQHRYL 496

  Fly   457 FDHREHTIFQHSLLGAVLGHEMNHAFEQEGILFDAAGN-------ESPVGLEIRESKPFRDAIKC 514
            :|.......::..||..:.|||.|.|:....|:|:.||       ::.||.|:.::        |
  Fly   497 WDDIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDNWSTQTKVGFELVKN--------C 553

  Fly   515 AEEQ------------PFVSLKERLADLNGLQLAYDAFFGLAH--DSRQFEYRPYAFEQEFTAPQ 565
            ..:|            ...|..|.:||..|:::|..|::....  :..:.|..|:..:   :..|
  Fly   554 LADQFSGMLYGNLRLRRLKSQAESIADNVGIRIAQSAYWKWLDQVEMEETESLPHMTQ---SPEQ 615

  Fly   566 LFHLSYAQFFCGSLPPVIA--------HDRDDERVNVSVGNLRQFAYDFNCETS----PSSVCEM 618
            ||.||.|||.|..:.|...        |...:.||...:.|...||..|.|..|    |.:.|.|
  Fly   616 LFFLSAAQFMCSDIYPERRANFVRNNFHPPYEARVFAMMINSPAFAEAFQCSNSSKMNPPNKCLM 680

  Fly   619 W 619
            :
  Fly   681 Y 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl10	NP_610787.1	GluZincin	41..608	CDD:472708	132/682 (19%)
Nepl17	NP_651641.1	M13	55..678	CDD:341056	135/695 (19%)