Protein Alignment Nepl10 and Ece2

DIOPT Version :10

• Sequence 1: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: XP_038944493.2
• Gene: Ece2 / 408243
• RGDID: 1303039
• Length: 789
• Species: Rattus norvegicus
• Alignment Length: 694
• Identity: 147/694 - (21%)
• Similarity: 257/694 - (37%)
• Gaps: 185/694 - (26%)

  Fly     6 LLCSCLVALFI-----PIQA--IVDINVATSNDIHNNLNRTTSPCTNFWNFACGRF-------SS 56
            ||..|||||::     |:.:  |.:..:..:..|..:|:|..|||.:|:.|:||.:       |.
  Rat   151 LLLGCLVALWVQYHRDPVHSTCITEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPSG 215

  Fly    57 ASKYVDNFERVEDQFATAMVEFMESHLGENDTL--APRLIKQMRQYYKAC--KEDTRKLHGNPRP 117
            .|:: :.|..:.||....:     .||.||.|.  :....::.|.:|.:|  .|...||...|.
  Rat   216 RSRW-NTFNSLWDQNQAIL-----KHLLENSTFNSSSEAERKTRSFYLSCLHLERIEKLGAKPL- 273

  Fly   118 EELVNQ---W-ILHP--------------------KKFLVY---------------GLNGVFIDE 143
            ::|:::   | |..|                    ..|.||               ..:|:|:..
  Rat   274 QDLIDKIGGWNITGPWDEDNFMEVLKAVAGTYRAAPFFTVYVGADSKSSNSNIIQVDQSGLFLPS 338

  Fly   144 R---VDVAANDS-----MRWVIQLRMPDPADRYSDRRVLQLMRLYEEAWYSMGVVKLVEKMHQL- 199
            |   ::..||:.     :.::::|.|.......|.|..:|               :::|...||
  Rat   339 RDYYLNRTANEKVLAAYLDYMVELGMLLGGQPTSTRAQMQ---------------QVLELEIQLA 388

  Fly   200 -----QDKYRAEYPVVYTWSFSELRQEIPIPH-----SFFIELLGVNHTEELYHLTFEVSDVEYL 254
                 ||:.|.|..:.:..|.|||:...|...     ||.:..|.:..:|.:.     |...|||
  Rat   389 TITVPQDQRRDEEKIYHKMSISELQTLAPSMDWLEFLSFLLSPLELGDSEPVV-----VYGTEYL 448

  Fly   255 RECFRCLRDFASEPK------------------DTYIRARQYVLVEE--SEPRERNPR--SCIHH 297
            ::....:.  .:||.                  |......|..|:|.  ...:...||  :||.:
  Rat   449 QQVSELIN--RTEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISN 511

  Fly   298 MRAYLPLGMNYIYDRFIYQNREEDTSKVLEILSTLKAAFGQYLDANRLQLTPNQLAYVRAKLEGI 362
            ....|...:..::.:..:..:.::.::  .::|.::|||.:.|: |.:.:........:.|.:.|
  Rat   512 TDDALGFALGSLFVKATFDRQSKEIAE--GMISEIRAAFEETLE-NLVWMDEKTRLAAKEKADAI 573

  Fly   363 QIKIGNLPEEKSPEFYNNHYGSANFSATNFLANLLEAFALRTRLQNAGLLARNSRVDLRHYYVND 427
            ...||.......|...::.|.....|..:|..|:|..:....::                  :.|
  Rat   574 YDMIGFPDFILEPRELDDVYDGYEVSEDSFFQNMLNLYNFSAKV------------------MAD 620

  Fly   428 NVRK-----------ARTSPFYENERNTITVPMEFLQWPLFDHREHTIFQHSLLGAVLGHEMNHA 481
            .:||           ...:.:|...:|.|..|...||.|.:.|..........:|.|:|||:.||
  Rat   621 QLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHA 685

  Fly   482 FEQEGILFDAAGNESPVGLEIRESKPFRDAIKCAEEQ------------PFVSLKERLADLNGLQ 534
            |:.:|..:|..||..| ..:......|::...|.|||            ...:|.|.:||..||:
  Rat   686 FDDQGREYDQEGNLRP-WWQNESLTAFQNHTACMEEQYNQYQVNGERLNGLQTLGENIADNGGLK 749

  Fly   535 LAYDAFFGLAHDSRQFEYRPYAFEQE-----FTAPQLFHLSYAQ 573
            .||:|:        :...|.:..||.     .|..|||.:.:||
  Rat   750 AAYNAY--------KAWLRKHGEEQPLPAVGLTNHQLFFVGFAQ 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl10	NP_610787.1	GluZincin	41..608	CDD:472708	135/652 (21%)
Ece2	XP_038944493.2	None