Protein Alignment Nepl10 and Nepl8

DIOPT Version :10

• Sequence 1: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Alignment Length: 688
• Identity: 147/688 - (21%)
• Similarity: 273/688 - (39%)
• Gaps: 167/688 - (24%)

  Fly     3 CLLLLCSCLVALFIPIQAIVDINVATSNDIHNNLNRTTSPCTNFWNFACGRFSSASKYVDNFERV 67
            ||||         :|:.| ...|....|.|.:::::..:||.|::|.|||::        |...:
  Fly     5 CLLL---------VPLVA-ASSNTRLLNGILSHVDKEANPCENYYNHACGQY--------NMRHI 51

  Fly    68 EDQFATAMVEFMESHLGENDTLAPRLIKQMRQ---------------------YYKACKEDTRKL 111
            :|.|.. :::.::..:.:|      |:|.|.:                     ||.:|:
  Fly    52 DDTFFD-IIQMLDHQVNQN------LVKLMDELEMSSQLPDFNVSSVDGKVLRYYLSCR------ 103

  Fly   112 HGNPRPEELVNQW--ILHPKKFLV---------------------------YGLNGVFIDERVDV 147
             |.||..:.::|:  ::.|.:.|.                           |||..||.:..|..
  Fly   104 -GAPRNMDSLSQYLKVISPGEGLTWPQFIPDGSSWPQENFKWLKALAHLHRYGLTNVFFNLEVVS 167

  Fly   148 AANDSMRWVIQLRMPD-------PADRYSDRRVLQLMRLYEEAWYSMGVVKLVEKMHQLQDKYRA 205
            ...::..::::|..|.       |........||.::::     .|..::.|..||..|:...:.
  Fly   168 NPRNASEYMVELNTPTFGEESQLPNSFIEILSVLYIIKV-----PSSEIITLARKMRTLELLLKT 227

  Fly   206 EYPVVYTWS--FSELRQ-EIPIPHS---FFIELLGVNHTEELYHLTFEVSDVEYLRECFRCLRDF 264
            ....:.|.:  :..:|. ::...|:   ||..|:|.:...||..|   |.:..|    |..|::.
  Fly   228 MINPIDTLNNRYISIRDFQMETGHNWQRFFEILIGSSAAPELQVL---VRNFRY----FTALKEL 285

  Fly   265 ASEPKD-----TYIRARQYVLVEESEPRERNPRSCIHHMRAYLPLGMNYIY-DRFIYQNREEDT- 322
             .:.:|     :||..|..:.:.:.....|....|:..:|..:.|..|.:| :||.    |:.|
  Fly   286 -MDKQDARLVASYIMTRFAIFLLDETMGGRESTECVSQVRRNMNLAANMLYKERFF----EDSTF 345

  Fly   323 -SKVLEILSTLKAAFGQYL---DANRLQLTPNQLAYVRAKLEGIQIKIGNLPE-EKSPEFYNNHY 382
             :.:|||....:....|:|   |.|.|:||..|:.:...|.|.|:|.:.|||: :....|...:|
  Fly   346 SANILEIKDIFEKLRHQFLLQVDQNHLELTALQMKFFVRKAEAIEINVVNLPKTDDLRHFIGQYY 410

  Fly   383 GSANF--SATNFLANLLEAFALRTRLQNAGLLARNSRVDLRHYYVNDNVRKARTSPFYENERNTI 445
            ....|  ...::....|:....||:    .:||::|:                   .:..|:|.:
  Fly   411 QDLQFPTGELDYHQEHLKVLQFRTQ----KMLAQSSK-------------------GHSEEQNIL 452

  Fly   446 T-----VPMEFLQWPLFDHREHTIFQHSLLGAVLGHEMNHAFEQEGILFDAAGNESPVGLEIRES 505
            |     .|:...| |.|......:|::||:|.::.|.:..||..|||...:.||:...     .|
  Fly   453 TYRSQAAPLPPPQ-PFFQLESEDVFKYSLMGYIMAHHLISAFATEGITIGSDGNDQSF-----RS 511

  Fly   506 KPFRDAIKCAEEQPFVSLKERLADLNGLQLAYDAFFGLAHDSRQFEYRPYAFEQEFTAPQLFHLS 570
            ..|.:|:.|..... .::.|.:.|:.||:|||..:..:|.:..:.::      ......|:|.|:
  Fly   512 HRFEEAVSCLSRNS-ENIDESMGDIAGLELAYFTYAKMAKNRNRLDF------THLPPEQIFFLN 569

  Fly   571 YAQFFCGSLPPVIAHDRDDERVNVSVGNLRQFAYDFNC 608
            ..|||||:...::.:..|..|:..::.....|...|.|
  Fly   570 VGQFFCGNSDMLVQYKEDQVRLQRAIEGFEPFDKAFGC 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl10	NP_610787.1	GluZincin	41..608	CDD:472708	137/648 (21%)
Nepl8	NP_609795.2	GluZincin	32..618	CDD:472708	138/651 (21%)