Protein Alignment Nepl10 and Nepl4

DIOPT Version :10

• Sequence 1: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 718
• Identity: 164/718 - (22%)
• Similarity: 293/718 - (40%)
• Gaps: 176/718 - (24%)

  Fly     4 LLLLCSCLVALFIPIQA---------IVDINVATSNDIH-----NNLNRTTSPCTNFWNFACGRF 54
            ||||.|......:|::|         :.:.| :|.|..|     :.::...:||.:|:.:|||::
  Fly     9 LLLLGSATCGSSVPVKANDPEQSCPYLGECN-STINQQHIDTLMSYVDSEKNPCEDFYAYACGKW 72

  Fly    55 -----SSASKYVDNFERVEDQFATAMVEFMESHLGENDTLAPR----LIKQMRQYYKAC----KE 106
                 |..:..:.:..::..|:....::.:      .:..||.    :..::..:|::|    |.
  Fly    73 RAKHGSHTTATMISESQINRQYEDLFLQLL------RNPSAPEYGYPMFAKVLAHYQSCIALEKP 131

  Fly   107 DTRKLHGNPRPEELVNQWIL------HPKKFLV----YGLNGVFIDERVDVAANDSMRWVIQLRM 161
            |.|      |..||:::.:|      |....|.    ||.:|.::  :|:|...::...:|.|.
  Fly   132 DLR------RYIELLDRDLLASLNSTHWMHLLAALGRYGYHGHYV--QVEVRWYNATHHMIFLL- 187

  Fly   162 PDPADRYSDRRVLQLMRLYE------EAWYSMGVVKLVEKMHQLQDKYRA-EYPVV--------- 210
              |.:|:.:..:.|  .:|:      .:|         ..:||||:::|: |..:|
  Fly   188 --PHNRHLNLSLTQ--DIYDALSQDGSSW---------PPLHQLQEQFRSLEQNLVRLAKPHSAD 239

  Fly   211 ---YTWSFSELRQEIPIPHSFFIELLGV--------NHTEELYHLTFEVSD-------VEYLREC 257
               ..:|..::|.|:|..|  :.|.|..        ||       .|:|.|       ||||...
  Fly   240 DTFRNYSLDQIRTEVPGLH--WDEALRTQLGRSVPGNH-------VFQVDDLDAIEGLVEYLNTV 295

  Fly   258 FRCLRDFASEPKDTYIRARQYV------LVE---------ESEPRERNPRSCIHHMRAYLPLGMN 307
                        ||.:..|..:      |:|         ||..|.|. |:||.|||..:.|.||
  Fly   296 ------------DTLLLNRYSLARFLSHLLELPHNPLATWESGQRSRG-RNCIRHMRRSVYLPMN 347

  Fly   308 YIYDRFIY-QNREEDTSKVLEILSTLKAAFGQYLDANRLQLTPNQLAYVRAKLEGIQIKIGNLPE 371
            |:|:|..| :.|..|...:..:...|::.....:..|...|:.:.:..::||:..::|.:||||.
  Fly   348 YVYERSFYSRRRHADELVIHSVFQQLQSQLELRVQHNAFNLSQDLVKSLQAKVHQMRINVGNLPP 412

  Fly   372 EKSPEFY---NNHYGSANFSATNFLANLLEAFALRTRLQNAGLLARNSRVDLRHYYVNDNVRKAR 433
            ..:.:||   :..:........|.|.:||..:.|...|::      :|..:.|..:.:.|:....
  Fly   413 NVTEQFYWDSDRRWSVGRDFYENHLNSLLYYYTLVADLES------SSDQEERDIWYSFNMHTPE 471

  Fly   434 ------TSPFYENERNTITVPMEFLQWPLFDHREHTIFQHSLLGAVLGHEMNHAFEQEGILFDAA 492
                  .:|::....|.|.||..:::.|.||........:..|...||||:.|||:.:.:.:||.
  Fly   472 FPDNIDATPYFYCLGNIIFVPYSYVKRPFFDANFWPALLYGDLANTLGHEIMHAFDTDLVDYDAQ 536

  Fly   493 GNESPVGLEIRESKPFRDAIKCAEEQPFVSLKERLADLNGLQLAYDAFFG--LAHDSRQFEYRPY 555
            ||......::.|.:.:..|:.|..... |.|.||.:|::|.:||...:.|  |.....
  Fly   537 GNLRNFSDQLGEVELYNGAVGCLNSSA-VMLNERTSDVSGSRLAMQTYGGDWLTRSGN------- 593

  Fly   556 AFEQEFTAPQLFHLSYAQFFCGSLPPVIAHDRDDERVNVSVGNLRQFAYDFNCET----SPSSVC 616
                    .:|:.|.:|.||||...... ||...:|:|.::|.:.|||..|.|..    :.:..|
  Fly   594 --------GRLYFLQFAHFFCGDEGDQY-HDSGSQRLNYALGQVPQFAEVFRCHVGSGMTSADQC 649

  Fly   617 EMW 619
            ..|
  Fly   650 PFW 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl10	NP_610787.1	GluZincin	41..608	CDD:472708	150/650 (23%)
Nepl4	NP_609019.1	GluZincin	59..649	CDD:472708	151/662 (23%)