Protein Alignment Nepl10 and Nepl3

DIOPT Version :10

• Sequence 1: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 684
• Identity: 148/684 - (21%)
• Similarity: 260/684 - (38%)
• Gaps: 161/684 - (23%)

  Fly     4 LLLLCSCLVALFIPIQAIVDINVATSNDIHNNLNRTTSPCTNFWNFACGRFSSASKYV--DNFER 66
            ||||||.:.:        .:.|:.....:.::::....||.||:|       |:.|.:  ..|..
  Fly    14 LLLLCSTVCS--------ANPNLEIMKRMLDDMDEKVEPCHNFYN-------SSQKNLKWHAFAT 63

  Fly    67 VEDQFATAMVEFMESHLGENDTLAPRLIKQMRQYYKACK-----------------EDTRKLHGN 114
            |.||| ..:.:.:|:.:.|..:...:|    ::.||.|.                 ||.......
  Fly    64 VSDQF-QLLFDGIENEVFEKHSFEEKL----QRLYKICSTMERPSLLRYFELVKPGEDLNWPFLT 123

  Fly   115 PR----PEELVNQWILHPKKFLVYGLNGVFIDERVDVAANDSMRWVIQLRMPDPADRYSDRRVLQ 175
            ||    |:|.. ||:....:...||.|        |:....|:|       .|| :..|.:.::.
  Fly   124 PRGGKWPKEKF-QWMEALARLRRYGFN--------DIMFGMSIR-------QDP-NSDSGQPIVV 171

  Fly   176 LMRLYE------EAWYSMGV-VKLVEKM----HQLQDKYRAEYPVVYTWSFSELRQEIPIPHSFF 229
            ..:.|:      |:..::|: .||.:::    :.:|:.|:::....:     ..|...|:.....
  Fly   172 FEKKYDSLFRFIESLQNIGLPPKLAKEIAPLDNAIQEMYKSDMKFEH-----YARDAAPVKRISL 231

  Fly   230 --IELLGVNHTEELYHLTF----------EVSDVEYLRECFRCLRDFASEPKDTYIRAR-----Q 277
              :|:.||:.|:.| .:.|          .|.::.|||.....:....|:....|:.||     .
  Fly   232 GQLEIYGVSLTKYL-EIVFGRPFSPDFVVHVENLYYLRGLQNLMTAVPSQVVANYLTARFSFYIM 295

  Fly   278 YVLVEESEPRERNPRSCIHHMRAYLPLGMNYIYDRFI--------YQNREEDTSKVLEILSTLKA 334
            :..::..:       ||:..||..:....|.:::..|        |||:..      :|...::.
  Fly   296 FTFMKHGD-------SCVTTMRQSMEFASNLLFEERILGRKKLRSYQNQAG------KIFDAIRQ 347

  Fly   335 AFGQYLDANRLQLTPNQLAYVRAKLEGIQIKIGNLPEEKS-PEFYNNHYGSANFSATNFLANL-L 397
            .....|:.|.|:|.|.:::.::.||.|:.:.|||||.:.. ..|...:|....|:....||.. |
  Fly   348 QLNIRLERNVLKLPPAEISLLQKKLNGLSLSIGNLPGKAGHRRFVTRYYKELEFADDEELATAHL 412

  Fly   398 EAFALRTRLQNAGLLARNSRVDLRHYYVNDNVRKARTSPFYENERNTITVPMEFLQWPLFDHREH 462
            :....|||.: ..||.:.:..|.|:...:..:........||...|||.|..:||....||...|
  Fly   413 KVLEHRTRAE-LSLLDQPNFKDRRYMLHSYPISNFFFETAYEENGNTIYVAYDFLADASFDPDSH 476

  Fly   463 TIFQHSLLGAVLGHEMNHAFEQEGI---------LFD-----AAGNESPVGLEIRESKPFRDAIK 513
            .||:.:.||...|.||..:|:....         |||     .||:|               .:.
  Fly   477 DIFKVTPLGIRFGLEMLKSFDLFNCKHHKVNMLQLFDDNQITTAGDE---------------CVS 526

  Fly   514 CAEEQPFVSLKERLADLNGLQLAYDAFFGLAHDSRQFEYRPYAFEQEFTAPQLFHLSYAQFFCGS 578
            ...:...:|.:::.  |..|.|.::|:|.   :..:|..|    :..||...|..|.:.:|...|
  Fly   527 AWTQDNLLSQRDQY--LVVLHLVHEAYFA---EGSKFSQR----QPNFTTMSLRELFFFRFGQSS 582

  Fly   579 LPPVIAHDRD----DERVNVSVGNLRQFAYDFNC 608
            ....:....|    ...:| |:..|..|...|||
  Fly   583 FGQTLYFGSDFVEGGSPIN-SLTRLPVFVRTFNC 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl10	NP_610787.1	GluZincin	41..608	CDD:472708	139/645 (22%)
Nepl3	NP_608904.1	GluZincin	42..>434	CDD:472708	92/440 (21%)