Protein Alignment Nepl10 and nep-6

DIOPT Version :10

• Sequence 1: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_494537.1
• Gene: nep-6 / 184628
• WormBaseID: WBGene00017550
• Length: 726
• Species: Caenorhabditis elegans
• Alignment Length: 711
• Identity: 151/711 - (21%)
• Similarity: 259/711 - (36%)
• Gaps: 209/711 - (29%)

  Fly    26 VATSNDIHNNLNRTTSPCTNFWNFACGRFSSASKYVDNFERVEDQFATAMVE--------FMESH 82
            |..::.:.|..:.:..||.:|:..|||::|            |.:.|...::        .:::.
 Worm    91 VTLADQLLNFQDPSVDPCQDFYKAACGKYS------------EHEVANRRLQKKDIIIQRMIKNF 143

  Fly    83 LGENDTLAPRLIKQMRQYYKACK--------------------EDTRKLHGNPRPEELVNQWILH 127
            |.:|:|...:....|||.|:.|:                    :|.:|:...|..::..::..|:
 Worm   144 LLKNETSESKSENVMRQVYRTCEGLKNEEIFNANMKTAFRELFKDIQKIGSWPAADKNWDETKLN 208

  Fly   128 PKKFLV---------YGLNGV------FIDERVDVAANDSMRWVIQL----------RMPDP--- 164
            ..:.|:         :||..:      |::...|:|.:..:....|.          ..||.
 Worm   209 LNEMLLNIVKLGSSNFGLFQIRPTEVPFLEVAPDMARSPKVSANFQQIIFDILEKNGLQPDENVI 273

  Fly   165 ADRYSDRRVLQLMRLYEEAWYSMGVVKLVEKMHQLQDKYRAEYPVVYTWSFSELRQEIPI--PHS 227
            ||...|                  .:.|.|.:.|....|.||     ...||:|:.::|.  ...
 Worm   274 ADDVED------------------YITLEETLSQYAYDYNAE-----KVQFSKLQAQVPSLKLEK 315

  Fly   228 FFIELLGVNHTEELY-----------HLTF--EVSDVEYLRECFRCLRDFASEPKDT---YI--- 273
            ...|::..|..:.|.           |..|  |..::|.|         ..|.||.|   |:
 Worm   316 IIEEMMNPNRKKLLVTKVKPRMVAHKHSLFFDEKMNLEKL---------LKSTPKRTLANYLIFY 371

  Fly   274 ---RARQYVLVEESEPRERNPRSCIHHMRAYLPLGMNYIYDRFIYQNREEDTSKVL-EILSTLKA 334
               .|...:.|.::..::||   |...:..|||.....:   |:..:.|:...|:: |:....|.
 Worm   372 YMDHAMNGLSVHDNVIKKRN---CEKLVIEYLPKASLRV---FVRNHFEKGNLKIVDEMAEETKK 430

  Fly   335 AFGQYL-DANRLQLTPNQLAYVRAKLEGIQIKIGNLPEEKSPEFYNNHYGSANFSATNFLANLLE 398
            :|.:.| ::..|.....:.|.:  |||.:...|| .|:|              |.....|..:.|
 Worm   431 SFIEMLQESTWLGADSKKNAIL--KLEKMGKMIG-YPKE--------------FEKKGALDKMFE 478

  Fly   399 AFALRTRLQNAGLLARNSRVDLRHYYVNDNVR-------------KARTSPFYENERNTITVPME 450
            ...|..:....|:|.:..|     :::...:.             ...|:.|| .:||.::..:.
 Worm   479 TLKLLPKDTLYGILKKIGR-----FHMEQGIEFVALETPMDPVLPVLMTNAFY-TDRNHLSFLVG 537

  Fly   451 FLQWPLFDHREHTIFQHSLLGAVLGHEMNHAFEQEGILFDAAGNESPVGLEIR------ESKPFR 509
            ::..||||.........:|.|.:|.||.:|.|:..||..|..|       |:|      :.|.:.
 Worm   538 YMDDPLFDATYPKYVNIALTGNILAHETSHGFDTAGIKRDENG-------EVRSWMKPEDLKEYG 595

  Fly   510 DAIKCAEEQ------PF--------VSLKERLADLNGLQLAYDAFFGLAHDSRQFEYRPYAFEQE 560
            ...:|..:|      |.        .:|.|.:||:.|:.:|:..|..|  ||.: |.:...||.|
 Worm   596 KKTQCLVDQYNEYDDPVFGKNLNGTTTLNEMVADMIGVTVAWKVFEKL--DSSK-EQKVIGFENE 657

  Fly   561 FTAPQLFHLSYAQFFCGSLPPVIA--------HDRDDERVNVSVGNLRQFAYDFNC-ETSP 612
             ...:|:..:.|..|| ||||..:        |...:.|||....|:.|||..||| |.||
 Worm   658 -NIDKLYFRAAALDFC-SLPPTTSLVEELTRVHPTGNFRVNGIFSNMPQFATAFNCPEGSP 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl10	NP_610787.1	GluZincin	41..608	CDD:472708	144/689 (21%)
nep-6	NP_494537.1	M13	105..724	CDD:341056	149/697 (21%)