Protein Alignment Nepl10 and nep-26

DIOPT Version :10

• Sequence 1: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001022540.1
• Gene: nep-26 / 174593
• WormBaseID: WBGene00014171
• Length: 807
• Species: Caenorhabditis elegans
• Alignment Length: 789
• Identity: 170/789 - (21%)
• Similarity: 295/789 - (37%)
• Gaps: 226/789 - (28%)

  Fly     2 GCLLL---------LCSCLVALFIPIQAIVDIN---VATSNDIHNNLNRTTSPCTNFWNFACGRF 54
            |||||         ..|..:|.|:..|.:...:   |.|::.:...::::..||.||:.||||.:
 Worm    74 GCLLLTVLVIFLFVTLSFAIACFLYYQTLPCTSEECVMTASRLLKRVDQSVEPCDNFYQFACGGW 138

  Fly    55 SSAS---KYVDNFERVEDQFATAMVEFMESHLGENDTLAP-------RLIKQMRQYYKACKE-DT 108
            .:.|   || |::..:.:...||..:.:::....||...|       |...:|   |:.|.: ||
 Worm   139 INQSVNLKY-DSWNTLYETQRTAHDQIVQAMHKINDGSYPLPTNAGERAAAKM---YEQCMDTDT 199

  Fly   109 RKLHGNPRPEELVNQ---WILHPKKFLVYGLNGVF-IDERVDVAANDSMRWVIQLRMPD---PAD 166
            .:..|....|..|::   |:...|       ||.. .:|..::..::..:...:..:.|   .|.
 Worm   200 LEQTGLHLWERFVDELGGWMPELK-------NGALEQEESFEIELDEDEKKRRRFEIEDIILSAF 257

  Fly   167 RYSDRRVLQLMRLYEEAWYSMGVVKLVEKMHQL-----------QDKY-------------RAEY 207
            .||         ::...|..:.|..|..|.|.:           .:||             :.|.
 Worm   258 NYS---------VFPLFWAGVEVNYLNSKEHLITIYEQLPILLAPEKYHYNKELTPEMIYGKMEG 313

  Fly   208 PVVYTWSFSELRQEIPIPHSFFIELLGVNHTEELYHLTFEVSDVEYLR-ECFRCLRDFASEPKDT 271
            |.| |.:..::.:|:.       .:||.:.|:|...:.  ::::.||. :.......|..|.|:.
 Worm   314 PPV-TRALQQVGEELS-------AVLGFDSTDEKVRMM--IANMIYLEYQITMAGSTFYKEKKER 368

  Fly   272 Y----IRARQYV------------LVEE----SEP------------------RERNPRSCIHHM 298
            |    :|..|.:            ||.|    |||                  :.:..||.:..:
 Worm   369 YTVVMLRELQEIAPAINWHYFLSRLVGENLSHSEPIALKTGTQWIPILSAIVEKLKQSRSGVAVL 433

  Fly   299 RAYLPLGMNYIYDRFIYQNREEDTSKVLEILSTLKAAFGQYLDANRLQLT---PNQLAYVRAKLE 360
            :.|:.  ...|.....|.:.:.....:...:|....|..|..:...|:|:   |..|..:..|::
 Worm   434 KNYVK--WKTIMFHLAYASPKCRDGLLWMAVSLYSGAASQRKEFCVLRLSGIFPLSLPSILRKID 496

  Fly   361 GI-----QIKIGNLPEEKSPEFYNNHYGSAN-FSATNFLANLL---------------------- 397
            ||     .:|......::..|.|.....|:| ||......|::
 Worm   497 GIDHTEKNVKAVQNIADRIQEKYEEMVRSSNLFSDRETRENVIDKVNNMTKFIGFPDAMRSDYEM 561

  Fly   398 --EAFALRTRLQNAGLLARNS-----------RVDLRHYYVNDNVRKARTSPFYENERNTITVPM 449
              ||..|...|..:.:|..:|           .||.|.:.   :.|.|.:.|.:..|||.:.:|.
 Worm   562 EKEAVRLHDTLFWSMVLGSSSVYKERLQRLRLPVDPRSWV---DTRPAISVPAHNYERNLVQIPF 623

  Fly   450 EFLQWPLFDHREHTIFQHSLLGAVLGHEMNHAFEQEGILFDAAGNESPVGL-----EIRESKPFR 509
            :.|:.|..|..:.....::.:|.::|||:.|||:.:|.|....||   :|:     .|||.|
 Worm   624 DSLRLPYADEHQLDFANYAGIGTIIGHELTHAFDGQGKLHGPTGN---LGVWWSTDSIREFK--- 682

  Fly   510 DAIKCAEEQPFV-----------------SLKERLADLNGLQLAYDAFFGLAHDSRQFEYRPYAF 557
                 |.||.||                 .|.|.:||..||::||:|:   ..:..|...|....
 Worm   683 -----AREQCFVKQYAGLMDSHDMNAAKEGLYENIADQVGLKVAYEAW---KSNGNQNSGRMPGL 739

  Fly   558 EQEFTAPQLFHLSYAQFFCG------SLPPVIAHDRDDERVNV--SVGNLRQFAYDFNCET---- 610
            | :::..|||.|:|.|.:|.      .|.|.:     :||:.:  |:.|..:||..:.|.:
 Worm   740 E-KYSQDQLFFLAYTQGWCALRSKSYKLQPHM-----EERIRMLGSLQNSPEFASAWKCSSESFM 798

  Fly   611 SPSSVCEMW 619
            :|...|.:|
 Worm   799 NPPDKCSIW 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl10	NP_610787.1	GluZincin	41..608	CDD:472708	155/721 (21%)
nep-26	NP_001022540.1	M13	124..805	CDD:341056	157/735 (21%)