Protein Alignment Nepl10 and nep-3

DIOPT Version :10

• Sequence 1: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_494679.2
• Gene: nep-3 / 173730
• WormBaseID: WBGene00016778
• Length: 634
• Species: Caenorhabditis elegans
• Alignment Length: 668
• Identity: 137/668 - (20%)
• Similarity: 244/668 - (36%)
• Gaps: 184/668 - (27%)

  Fly    32 IHNNLN---RTTSPCTNFWNFACGRFSSASKYVDNFERVEDQFATAMVE-----FMESHLGENDT 88
            :|..||   .:..||.||:..|||::        |...|.|...||..:     .:...|.:|.:
 Worm    71 VHQLLNFQDPSVDPCENFYQAACGKY--------NEHNVIDGSRTAQKQQIVKRLIRDFLHKNQS 127

  Fly    89 LAPRLIKQMRQYYKACKE-DTRKLHGNPRPEELVNQWILHPKKFLVYGLNGVFIDERVDVAANDS 152
            ...:....|:..|:.||| .|.|:.||   :.|:.:..::.:|...:.:    :||..|
 Worm   128 STSKSENSMKLLYEKCKEAKTIKVLGN---QNLLQEIFMNIQKIGSWPV----LDENWD------ 179

  Fly   153 MRWVIQLRMPDPADRYS-DRRVLQLMRLYEEAWYSMGVVKLVEKMHQLQDKYRAEYPVVYTWSFS 216
                        ..::: :..:|.|:||                             .|..:.|.
 Worm   180 ------------GKKFNLNEMLLSLIRL-----------------------------GVSNFGFF 203

  Fly   217 ELRQEIPIPHSFFIELLGVNHTEELYHLTFEVSDVEYLRECFRCLRDFASEPKDTYIR--ARQYV 279
                ||.|....|:|:....:.....:|:..:|.| :|...|        :|..|.|.  .|:|.
 Worm   204 ----EIIISSDAFVEIKPARNFPTRENLSDIISKV-FLGNGF--------QPNITAIENDLREYE 255

  Fly   280 -LVEESEPRER----NP-RSCIHHMRAYLPLGMNYIYDRFIYQNR---EEDTSKVLEIL--STLK 333
             |..|.:..||    .| ||.:::      |..||:....:...|   |:....|::.|  ::.:
 Worm   256 NLQRELKSLERLIQTTPNRSLVNY------LIFNYLKSVMLEYKRLPEEQCEGVVIDFLPRASTR 314

  Fly   334 AAFGQYLD-ANRLQLTPNQLAYVRAKLEGIQIKIGNLPEEKS----------------------- 374
            .....:|| .||        .||...:|.:::...::.:|.:
 Worm   315 VFVQNFLDKENR--------KYVAGMIEDVKMGFIDMIQESTWLNEESKKVAVQKVKNIKSMIGY 371

  Fly   375 PEFY------NNHYGSANFSATNFLANLLEAFALRTRLQNAGLLARNSRVDLRHYYVNDNVRKAR 433
            |:|:      :..:...|...|:....::......|..|....:|....:|.|...::.|.
 Worm   372 PDFFEPPGTLDRSFKDLNIEQTDSYHTIVRKIQKFTNEQCMEFVASEIPLDPRQPILHANA---- 432

  Fly   434 TSPFYENERNTITVPMEFLQWPLFDHREHTIFQHSLLGAVLGHEMNHAFEQEGILFDAAGNESPV 498
               ||:| .|.:.:....|..|:||.........:::|.||.||:.|||:..||.:|.||.:. :
 Worm   433 ---FYQN-TNFLAILAPVLDDPIFDTTFPRYVNLAVIGNVLAHEIGHAFDHTGINYDDAGQQR-I 492

  Fly   499 GLEIRESKPFRDAIKCA-------EEQPF-------VSLKERLADLNGLQLAYDAF--FGLAHDS 547
            .|...:|:.:...::|.       ::..|       .:|.|..||..|::.|:..|  ..|:::|
 Worm   493 WLTPEDSEEYGKRLRCLLRQHDEYDDPDFGRNLNGSKTLHEISADRFGVEAAWRTFKKLDLSNES 557

  Fly   548 RQFEYRPYAFEQEFTAPQLFHLSYAQFFCGSLPPV-------IAHDRDDERVNVSVGNLRQFAYD 605
            ....:      |.|...||:..:.|..:|......       ..|..::.|||....|:.|||..
 Worm   558 EIVGF------QNFNIDQLYFRTAALIWCRQRDTTDLQYALQREHPTNNFRVNGIYANMPQFAET 616

  Fly   606 FNC----ETSPSSVCEMW 619
            |||    ..:|...|:::
 Worm   617 FNCPLGSPMNPKKKCDLF 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl10	NP_610787.1	GluZincin	41..608	CDD:472708	130/639 (20%)
nep-3	NP_494679.2	M13	82..631	CDD:341056	133/652 (20%)