Protein Alignment Nepl10 and nep-9

DIOPT Version :10

• Sequence 1: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_494531.2
• Gene: nep-9 / 173683
• WormBaseID: WBGene00017554
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 662
• Identity: 128/662 - (19%)
• Similarity: 229/662 - (34%)
• Gaps: 200/662 - (30%)

  Fly    51 CGRFSSASKYVDNFERVEDQFATAMVE--FMESHLGENDTLAPRLIKQMRQYYKACKEDTRKL-- 111
            |...|..:.|:|.|:.::...:..::|  :.:|....:|.:| :|:|.....:...|.:.|||
 Worm   146 CDELSRNTSYLDIFKDIKKIGSWPVLEHNWKDSMFNLDDVIA-KLVKLGSTDFGLFKLELRKLAF 209

  Fly   112 -----HGNPRPEELVNQWILHPKKFLVYGLNGVFIDERVDVAANDSMRWVIQLRMPDPADRYSDR 171
                 ..:.:.|:.::|  |......:...||:..|.:               .:.|....|||.
 Worm   210 GHFAVFVSSKQEQNIHQ--LEKTILGILKANGIQQDRK---------------ELSDDLKDYSDF 257

  Fly   172 RVLQLMRLYEEAWY------------SMGVVKLVEKMHQLQDKYRAEYPVVYTWSFSELRQEIPI 224
            : ..|...|:|..|            ::|:..|..:|.........         |:.:.|...|
 Worm   258 K-NHLKEFYQEETYIEYRLYAGSIVENLGISSLTTQMALKSTGLDV---------FNHVNQRTLI 312

  Fly   225 PHS--FFIE--LLG--VNHTEE-------LYH----LTFEVSDVEYLRECFRCL----------- 261
            .:|  ||.|  .||  :..|.:       ::|    :|.::::.  .:.|...|
 Worm   313 TNSSLFFGEENNLGMIIQKTPKRTLANFLIFHFIDVMTTDLANA--TKACKETLIDLLPRASIQV 375

  Fly   262 --RDFASE-PKDTYIRARQYVLVEESEPRERNPRSCIHHMRAYLPLGMNYIYDRFIYQNREEDTS 323
              |:|.:| .:|..::..|.:..:.:|..:.:|.....|:          ::|       .|:..
 Worm   376 LSRNFVNEDAQDDMVKMAQDLKTKITEMIDNSPFFTKFHL----------VFD-------AEEQK 423

  Fly   324 KVLEILSTLKAAFGQY------LDANRLQLTPNQLAYVRAKLEGIQIKIGNLPEEKSPEFYNNHY 382
            |:::.:..: ....:|      .|..||.|||:...|     ..|| |:..|..|:..|    |.
 Worm   424 KLIQKVKAI-GIVTEYPQEVLDRDFERLNLTPSDSIY-----RTIQ-KLRRLRSEQLIE----HL 477

  Fly   383 GSANFSATNFLANLLEAFALRTRLQNAGLLARNSRVDLRHYYVNDNVRKARTSPFYENERNTITV 447
            | .:...|:            ||:..                          |..|:...|.:|:
 Worm   478 G-GDLDPTD------------TRVWG--------------------------SAHYDQTTNNLTI 503

  Fly   448 PMEFLQWPLFDHREHTIFQHSLLGAVLGHEMNHAFEQEGILFDAAGNESPVGLEIRESKPFRDAI 512
            ....:..|.||..........|:|.:||.|:..:.:...|..|..| ::...|:....|.|.:.:
 Worm   504 FAPIIDGPYFDTSYPNYVNQFLMGFILGRELGRSLDSVRIRKDEKG-QTENWLKPESLKRFDEHL 567

  Fly   513 KCAEEQ------PFVS-------------LKERLADLNGLQLAYDAFFGLAHDSRQFEYRPYAFE 558
            ||..|:      |..|             ..|..||..|.:.::.||..|  |.:..|..
 Worm   568 KCWAEKYDKSADPLKSESKGIRQIEGRYIQNEMFADFIGHEASWRAFMKL--DVKNEEVL----- 625

  Fly   559 QEFTAPQLFHLSY---AQFFCGSLPPVIA---------HDRDDERVNVSVGNLRQFAYDFNC--- 608
            :.|...:|..:.:   |.:||  .||..:         |.....|||.:..|:.|||..|.|
 Worm   626 ETFKVIKLRRMFFNVQALYFC--RPPSGSTDWLSYQEHHQHYSFRVNGAFKNMPQFALAFECASD 688

  Fly   609 -ETSPSSVCEMW 619
             :.:|.:.|.|:
 Worm   689 DDMNPQNKCSMF 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl10	NP_610787.1	GluZincin	41..608	CDD:472708	124/645 (19%)
nep-9	NP_494531.2	GluZincin	87..698	CDD:472708	126/658 (19%)