Protein Alignment Nepl10 and Nep1

DIOPT Version :10

• Sequence 1: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: XP_553645.4
• Gene: Nep1 / 1279203
• VectorBaseID: AGAMI1_011171
• Length: 869
• Species: Anopheles gambiae
• Alignment Length: 736
• Identity: 171/736 - (23%)
• Similarity: 279/736 - (37%)
• Gaps: 199/736 - (27%)

  Fly    21 IVDINVATSNDIHNNLNRTTSPCTNFWNFACGRFSSA------SKYVDNFERVEDQFATAMVEFM 79
            :.|..|.|::.:...::||..||.:|:.||||.::..      ...:..||.:.||....:...:
Mosquito   196 LTDECVRTASSLLAAMDRTADPCKDFFQFACGTWNKMHVIPEDRSSISTFEVLADQQQAILKGVL 260

  Fly    80 ESHLGENDTLAPRLIKQMRQYYKAC--------------KEDTRKLHGNPRPEELVNQWILHPK- 129
            |..:.:.|.   |..|:.:.:||:|              ::..:||.|.|..|:   .|.: |.
Mosquito   261 EEPVNKEDN---RATKKAKAFYKSCMNLEQIRLLDVQALRKSLKKLGGWPVIEK---NWTV-PST 318

  Fly   130 --KFLVYGLNGVFIDE----RVDVAAND---SMRWVIQ-----LRMPDPADRYSDRRVLQLMRLY 180
              :.|:..|.|.: ||    .:.|.|:|   ||. :||     |.:|. .|.|........|:.|
Mosquito   319 SIEHLLGKLTGEY-DEPGLVELYVGADDKNSSMN-IIQVDQLLLALPS-RDYYLKESSEGDMKAY 380

  Fly   181 EEAWYSMGVV------KLVEKMHQ------------LQDKYRAEYPVVYT-WSFSELRQEIP-IP 225
            ......:.::      |..|::.:            |.:..|.:...:|| .:..||::.:| |.
Mosquito   381 HRYMTQIAILMGADKDKAAEELQRIVEFEVRLANATLPEADRHDTSAIYTKITLPELQRRVPQIN 445

  Fly   226 HSFFIE-LLGV-----NHTEELYHLTFEVSDVEYLRE----------CFRCLRDFASEPKDTY-- 272
            ...::: .||.     |.:...|.:.:.|...:.||:          .:|.:....:...|.|
Mosquito   446 WKEYLQTTLGTVALHPNESIVSYAMPYLVELGKILRDTDRRIVHNYAIWRLVMSIMTHMIDDYQK 510

  Fly   273 --IRARQYVLVEESEPRERNPRS-CIH--HMRAYLPLGMNYIYDRFIYQNREEDTSKVLEILSTL 332
              :..|:.:|..:|   |||..| |:.  :.:..:.:|..:|.|.|    .:|.....|.::.|:
Mosquito   511 ERVEFRRKLLGIQS---ERNRWSQCVEWTNKKLGMAVGALFIRDNF----NQESKETALTMIHTI 568

  Fly   333 KAAFGQYL-------DANRLQLTPNQLAYVRAKLEGIQIKIGNLPEEKSPEFYNN------HYGS 384
            :.||.:.|       |..|        |..:.|.:.:..:||      .|:...|      .|.:
Mosquito   569 REAFNELLADIDWMDDETR--------AVAKEKADAMNERIG------YPDILTNADELEKEYVN 619

  Fly   385 ANFSATNFLANLLEAFALRTRLQNAGLLARNSRVDLRHYYVNDNVRKARTSPFYENERNTITVPM 449
            .......||.|:|........ :|..||.:  .||...:.....|..|    ||...:|.|..|.
Mosquito   620 LTIHGGLFLENILSILKWEAE-RNLQLLRK--PVDKNKWATEPAVVNA----FYNPNKNDIVFPA 677

  Fly   450 EFLQWPLFDHREHTIFQHSL----LGAVLGHEMNHAFEQEGILFDAAG------NESPVGLEIRE 504
            ..|| |||..:.   |..||    :|.|:|||:.|.|:.:|..||..|      |.:.:
Mosquito   678 GILQ-PLFYSQN---FPKSLNYGGIGVVIGHEITHGFDDKGRQFDKDGNMMQWWNNATI------ 732

  Fly   505 SKPFRDAIKCAEEQPFVSLK---------------ERLADLNGLQLAYDAFFGLAHDSRQFEYRP 554
             |.||:..:|..:| :...|               |.:||..||:.:|.|            ||.
Mosquito   733 -KTFRERAQCIIDQ-YSRYKIDEVGLYMDGRMTQGENIADNGGLKQSYRA------------YRK 783

  Fly   555 YAFEQ---------EFTAPQLFHLSYAQFFCGSLPPVIA--------HDRDDERVNVSVGNLRQF 602
            :..:.         ..|..|||.|:|||.:|||:.|..|        |.....||...:.|.|.|
Mosquito   784 WVSQHGSEPDLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSSVHSPGIIRVIGPLSNSRDF 848

  Fly   603 AYDFNC----ETSPSSVCEMW 619
            |..:.|    ..:|.|.|.:|
Mosquito   849 AEAYRCPLGSPMNPVSKCSVW 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl10	NP_610787.1	GluZincin	41..608	CDD:472708	161/699 (23%)
Nep1	XP_553645.4	None