DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8545 and l(2)10685

DIOPT Version :9

Sequence 1:	NP_610786.2	Gene:	CG8545 / 36365	FlyBaseID:	FBgn0033741	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_608573.1	Gene:	l(2)10685 / 33293	FlyBaseID:	FBgn0283525	Length:	503	Species:	Drosophila melanogaster

Alignment Length:	501	Identity:	108/501 - (21%)
Similarity:	178/501 - (35%)	Gaps:	166/501 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 GDDEEG---LESDDDTAQVGKLADLSDDDDANSDDDFDISGE---EDGAQADSDEEEDEDDD--- 227
            ||.|:.   ||| |....:..|.:|:.|...:|.:.....|:   |..::.|:...:.::.:
  Fly    72 GDTEQTCAMLES-DGAINMKSLINLAQDRVKDSTETVPEQGKSRHEIESKLDALLRKQQEREVAS 135

  Fly   228 ---DDDDDDDDDKLPIERANKKLKKREAEEAQLADDEMLETVDKQDVFQLPVEGEETEKDLTLQE 289
               ...:|.....||:|     ||....||.|   .|.:....||.:      .:..|:|:.|.|
  Fly   136 IYPSSPEDGSSAPLPLE-----LKFDNVEEDQ---PEQVNNPFKQSL------TKALEEDVKLDE 186

  Fly   290 VQQRIKDVSLVLSDFKRYRQADRSRGEYIDLLRRDLCLYYSYNEFLMEKLMDMLPLTELMEYLEA 354
              .|:.|..........|..|...:|                    ||   |.:..:|..:|.:.
  Fly   187 --HRLVDPQFGTGGLYEYMPAHSIKG--------------------ME---DWVAESEHYKYYQT 226

  Fly   355 SEIARPLTIRTNTLKTRRRDLAGALINRGVNLDPLGKWTKVGLVVFNSQVPLGATPEYLA----- 414
            | ...||.|...                                      |....||:|:
  Fly   227 S-ADFPLAIEPE--------------------------------------PSFHYPEHLSLYTYE 252

  Fly   415 ------------------GHYMIQGASSLLPVMALAPQENERILDMCSAPGGKG------SHIAS 455
                              .|:|:.|||: ||.:.|..:..||:||.|::||||.      .|:..
  Fly   253 MGNCSDFKGPKKCMTGVLSHFMMDGAST-LPPLFLQVKPGERVLDACASPGGKSLLMLQTLHLDH 316

  Fly   456 IMKNTGVLFANDSNRDRIKAIVANF-----HRLGIVNAVVSCEDGTKFRNI--MTGFDRVLLDAP 513
            ::.|.    ..:|..::::.::..:     .|......::|..|.   ||:  ...||::|:|.|
  Fly   317 LVCND----IQESRLNKLRKVMQEYLFDYKERWAGKRLILSQSDA---RNLDQYEQFDKILVDVP 374

  Fly   514 CTGTGVV--SKDPSV-KTTKSEVDVQRCYNLQRKLLLTAIDCTDAKSSTGGYIVYSTCSVLPEEN 575
            ||....|  .:|.:: |.|:.: :..|...||..:|...:...    ..||.:||||||:.|.:|
  Fly   375 CTTDRHVLNEQDNNIFKPTRIK-ERLRIPELQAGILANCLRLL----RPGGSLVYSTCSLSPIQN 434

  Fly   576 EWVIDYALKK---------------RNVKLV--------PTGLDFG 598
            :.|:..||:|               |:..|.        |.||.:|
  Fly   435 DGVVHMALQKVFTEYGITTTIKDLSRHTALFSDVFKFEHPKGLKYG 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8545	NP_610786.2	Methyltr_RsmF_N	333..424	CDD:293730	17/113 (15%)
		nop2p	363..637	CDD:188051	65/298 (22%)
		Nol1_Nop2_Fmu	428..636	CDD:279522	53/210 (25%)
l(2)10685	NP_608573.1	AdoMet_MTases	283..499	CDD:302624	53/210 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0144
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810