Protein Alignment CG8545 and Nop2

DIOPT Version :9

• Sequence 1: NP_610786.2
• Gene: CG8545 / 36365
• FlyBaseID: FBgn0033741
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: NP_001178714.1
• Gene: Nop2 / 314969
• RGDID: 1304616
• Length: 772
• Species: Rattus norvegicus
• Alignment Length: 911
• Identity: 366/911 - (40%)
• Similarity: 497/911 - (54%)
• Gaps: 167/911 - (18%)

  Fly     1 MGRKAEYSEKPKKGPGRKARKQGPPVFRKQSFAPM--EEEDKKLSHRQKQRFVKREQKKVVQKAK 63
            ||||.:.::|.|:|||||||||.........|.|.  :|..|:||.|.::|..||....|
  Rat     1 MGRKLDPTKKEKRGPGRKARKQKGAETELIRFLPAAGDENFKRLSSRARKRAAKRRSGSV----- 60

  Fly    64 LQEKRAKGKLPQPAKRKTAYNSDSDPEDNEEEPQVASSDEEVPQLVPAPKGQKATAPKGFTDDND 128
                    ::|:|.|                .|.:.:...|:|:.....:|:|..||...:|.:
  Rat    61 --------EVPKPNK----------------SPGIKTLPGELPKGAVQVRGKKRPAPIQNSDGD- 100

  Fly   129 AWLKPKKQQKQPETESEEEEEED----------EESEEDSEDELGEECEEEEEGDDEEGLESDDD 183
                          |.|:.||||          |:|.||..|:.|.:.|     |:||.|...:.
  Rat   101 --------------EEEDSEEEDVVTQGELWGSEDSSEDMVDDYGADSE-----DEEEKLLPIER 146

  Fly   184 TAQVGKLADLSDDDDANSDDDFDISGEEDGAQ-ADSDEEEDEDDDDDDDDDDDDKLPIERANKKL 247
            .|...|..|                 ..||.| ::.|.:|||....:.....|||
  Rat   147 AALKQKARD-----------------PADGTQWSEEDTDEDEGVTPESHPRKDDK---------- 184

  Fly   248 KKREAEEAQLADDEMLETVDKQDVFQLPVEGEETEKDL---TLQEVQQRIKDVSLVLSDFKRYRQ 309
                      |:.::...|::::.|.||..| :|::|.   .||.|.:||:|:..||.||...|:
  Rat   185 ----------AEGDLQINVEEEEAFVLPPAG-QTDQDAQTPDLQRVHKRIQDIVGVLRDFGAQRE 238

  Fly   310 ADRSRGEYIDLLRRDLCLYYSYNEFLMEKLMDMLPLTELMEYLEASEIARPLTIRTNTLKTRRRD 374
            ..|||.||:..|::||..||||.:||:.|||::.||:||:|:|||:|:.||:|:|||||||||||
  Rat   239 EGRSRTEYLSQLQKDLATYYSYGDFLLSKLMELFPLSELIEFLEANEVPRPITLRTNTLKTRRRD 303

  Fly   375 LAGALINRGVNLDPLGKWTKVGLVVFNSQVPLGATPEYLAGHYMIQGASSLLPVMALAPQENERI 439
            ||.|||||||||||||||:|.||||::|.||:||||||||||||:|||||:||||||||||:|||
  Rat   304 LAQALINRGVNLDPLGKWSKSGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERI 368

  Fly   440 LDMCSAPGGKGSHIASIMKNTGVLFANDSNRDRIKAIVANFHRLGIVNAVVSCEDGTKFRNIMTG 504
            ||||.|||||.|:||.:||||||:.|||:|.:|:|::|.|.||||:.|.:||..||.:|..::.|
  Rat   369 LDMCCAPGGKTSYIAQLMKNTGVILANDANAERLKSVVGNLHRLGVTNTIVSHYDGRQFPKVVGG 433

  Fly   505 FDRVLLDAPCTGTGVVSKDPSVKTTKSEVDVQRCYNLQRKLLLTAIDCTDAKSSTGGYIVYSTCS 569
            ||||||||||:||||:||||:|||.|.|.|:|||.:||::|||:|||..:|.|.||||:||.|||
  Rat   434 FDRVLLDAPCSGTGVISKDPAVKTNKDEKDIQRCAHLQKELLLSAIDSVNAASKTGGYLVYCTCS 498

  Fly   570 VLPEENEWVIDYALKKRNVKLVPTGLDFGVEGFTKFRQHRFHPSLNLTKRYYPHTHNMDGFYVAK 634
            :..||||||:|||||||||:|||||||||.||||:||:.||||:|..|:|:||||||||||::||
  Rat   499 ITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFRERRFHPTLRATRRFYPHTHNMDGFFIAK 563

  Fly   635 LKKFSNTIPITKEQQEEDEKQLDEAIEADATTEAAAESEEVEEEVASKEKGPRKLLGKRAGKPSF 699
            .|||||:||                                     ....|     ...||.|:.
  Rat   564 FKKFSNSIP-------------------------------------QPHSG-----NSAAGTPTE 586

  Fly   700 TEIEQELKKKKREES----KTKYVAKVFEQPVKKPKPEKPAEKKNEKSQAPDKQTNSSESPSKSA 760
            .:::.::..|....|    |....||..:|.|.:...:||.:|.|..|:.|...|..| .|:...
  Rat   587 PDLKGQVTPKSENSSQPTKKAHGAAKAKQQLVGQQHSKKPFQKMNGISKGPGLPTEPS-VPNVQV 650

  Fly   761 PKQKQTNGKTTVSNSDAKSFNKKNKGSQPKENGAGSPAKPDDNKPTTNGTNSPSKSAIKETKTKP 825
            ..:.|.:..:.|         |:.:..:.|:.|....|.|    |......:|:.....|....|
  Rat   651 SARPQESSLSDV---------KRKRAGKLKQRGPKQSAPP----PKVGDLGTPAMQTPSEISATP 702

  Fly   826 QPKGKQSPKGNAKLAKAPRVDIDDVPILEGKPIKKQNKLKQKSKQIGQLKKSTAGANAGKKQKFK 890
            :||   || |.||..:..:.::.:.|......:|:....|:.|........||....|.:::...
  Rat   703 RPK---SP-GKAKKREEVKQELPEQPAKGTASLKEDAAPKRLSSPTTAHHSSTRPPPAKRRKSMT 763

  Fly   891 K 891
            |
  Rat   764 K 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8545	NP_610786.2	Methyltr_RsmF_N	333..424	CDD:293730	68/90 (76%)
		nop2p	363..637	CDD:188051	198/273 (73%)
		Nol1_Nop2_Fmu	428..636	CDD:279522	143/207 (69%)
Nop2	NP_001178714.1	Methyltr_RsmF_N	<279..353	CDD:293730	59/73 (81%)
		nop2p	292..566	CDD:188051	198/273 (73%)
		Nol1_Nop2_Fmu	357..565	CDD:279522	143/207 (69%)
		PRK10905	573..>761	CDD:236792	45/210 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334704
Domainoid	1	1.000	317	1.000	Domainoid score	I1226
eggNOG	1	0.900	-	-		E1_COG0144
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	592	1.000	Inparanoid score	I948
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003697
OrthoInspector	1	1.000	-	-		oto97191
orthoMCL	1	0.900	-	-		OOG6_100487
Panther	1	1.100	-	-	LDO	PTHR22807
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2562
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.750